Mehdi Zoha, Shahbaz Hareem, Owais Aatika, Hasan Syeda Ushna, Nasr Ifrah, Jahangir Ahmed, Zubair Nashmia, Abdul Khaliq Syed Abdullah, Khalid Maria, Shahbaz Sana, Qureshi Momina, Hasan Raazia, Fasih Muhammad, Khalid Adeel, Hasan Danial, Nigar Soofia
Internal Medicine, Dow University of Health Sciences (DUHS), Karachi, PAK.
Cureus. 2019 Feb 12;11(2):e4054. doi: 10.7759/cureus.4054.
Background Chikungunya fever (CHIKF) is an infectious illness spread by the bite of mosquitoes and caused by an arbovirus known as Chikungunya virus (CHIKV). This disease has become an epidemic in Karachi and various other cities of Pakistan, affecting a large population, especially those from poor, socioeconomically underdeveloped areas. It is proving to be a severe and alarming cause of debility due to its prolonged detrimental effects on the joints. A significant number of cases are reported daily in different hospitals of Karachi, with Civil Hospital being one of the major tertiary care hospitals. The aim of this study is to determine the frequency and symptoms of chikungunya as well as to assess the participants' awareness about the spread and preventive measures of this disease. Methods This is a cross-sectional study that was carried out in Civil Hospital Karachi by approaching patients in the out-patient department (OPD) and the emergency department with complaints of fever and joint pain. All the data was collected via a pre-coded questionnaire during May-June 2017 by taking prior informed verbal consent and were analyzed through Statistical Package for the Social Sciences (SPSS) version 22 software. Results The age group most affected by this disease was the 21-30 years range, which represented almost a quarter of the cases (n=83, 32.17%). Majority of the respondents (n=214, 82.95%) had heard of the disease, mainly due to their own prior experience with it (n=100, 38.76%). Lethargy (n=219, 84.88%), difficulty in walking (n=213, 82.56%), and headache (n=209, 81.01%) were the major symptoms reported apart from fever (n=258, 100.00%) and arthralgia (n=258, 100.00%). Conclusion CHIKF is proving to be a great threat to people as it impairs their quality of life to a great extent. The recent outbreak of chikungunya has victimized a considerable population of Karachi. This study mainly assessed the severity of the disease and its symptoms as well as the lack of awareness among patients. Proper and effective preventive measures can further help to eradicate this disease on a large scale and prevent future epidemics.
背景 基孔肯雅热(CHIKF)是一种由蚊子叮咬传播的传染病,由一种名为基孔肯雅病毒(CHIKV)的虫媒病毒引起。这种疾病已在卡拉奇和巴基斯坦其他各个城市流行,影响了大量人口,尤其是来自贫困、社会经济欠发达地区的人群。由于其对关节的长期有害影响,它正被证明是导致身体虚弱的一个严重且令人担忧的原因。卡拉奇的不同医院每天都报告大量病例,市民医院是主要的三级护理医院之一。本研究的目的是确定基孔肯雅热的发病频率和症状,并评估参与者对这种疾病的传播和预防措施的认识。方法 这是一项横断面研究,在卡拉奇市民医院通过接触门诊(OPD)和急诊科有发热和关节疼痛主诉的患者进行。所有数据在2017年5月至6月期间通过预先编码的问卷收集,事先获得口头知情同意,并通过社会科学统计软件包(SPSS)22版软件进行分析。结果 受这种疾病影响最严重的年龄组是21至30岁,几乎占病例的四分之一(n = 83,32.17%)。大多数受访者(n = 214,82.95%)听说过这种疾病,主要是因为他们自己之前有过患病经历(n = 100,38.76%)。除了发热(n = 258,100.00%)和关节痛(n = 258,100.00%)外,嗜睡(n = 219,84.88%)、行走困难(n = 213,82.56%)和头痛(n = 209,81.01%)是报告的主要症状。结论 事实证明,基孔肯雅热对人们构成了巨大威胁,因为它在很大程度上损害了他们的生活质量。最近基孔肯雅热的爆发使卡拉奇的相当一部分人口成为受害者。本研究主要评估了该疾病的严重程度及其症状以及患者中缺乏认识的情况。适当有效的预防措施可以进一步有助于大规模根除这种疾病并预防未来的疫情。