Physical Examination Center, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.
Department of Epidemiology and Biostatistics, School of Public Health, Capital Medical University, Beijing, 100069, China.
Curr Med Sci. 2019 Apr;39(2):330-336. doi: 10.1007/s11596-019-2039-x. Epub 2019 Apr 23.
A host of studies found waist-to-height ratio (WHtR) having higher diagnostic value than other abdominal obesity anthropometric indicators for metabolic disorders. But the cut-off points are still not consistent. This study was aimed to explore the optimal cut-off point of WHtR in Chinese population and identify the association between WHtR and cluster of metabolic risk factors. In total, 13379 Han adults (7553 men and 5726 women) from over 40 institutions who took physical examination in Xuanwu Hospital of Capital Medical University between January 2014 and January 2015 were involved in this cross-sectional study. Subjects with two or more components of metabolic syndrome (MetS) were considered to have multiple risk factors. Optimal cut-off points of WHtR for cluster of metabolic risk factors were analyzed by receiver operating characteristic (ROC) curve analysis. The optimal cut-off points of WHtR were 0.51 for men and 0.49 for women. People with elevated WHtR had higher levels of metabolic risk factors. And the prevalence of individual and clusters of 5 risk factors were all higher among WHtR-defined abdominal obesity people than in normal subjects. The optimal cut-off points of WHtR were 0.51 for men and 0.49 for women. In conclusion, people with elevated WHtR are susceptible to cluster of metabolic risk factors.
大量研究发现,腰高比(WHtR)对于代谢紊乱等腹部肥胖人体测量指标具有更高的诊断价值。但截止值仍不一致。本研究旨在探讨中国人 WHtR 的最佳截断点,并确定 WHtR 与代谢风险因素群之间的关系。共有来自首都医科大学宣武医院 40 余家机构的 13379 名汉族成年人(男性 7553 名,女性 5726 名)参加了这项横断面研究。具有两种或两种以上代谢综合征(MetS)成分的受试者被认为具有多种危险因素。通过受试者工作特征(ROC)曲线分析,对 WHtR 与代谢风险因素群相关的最佳截断点进行分析。WHtR 的最佳截断点为男性 0.51,女性 0.49。WHtR 升高者具有更高水平的代谢危险因素。WHtR 定义的腹型肥胖人群中,单个和 5 个危险因素群的患病率均高于正常人群。WHtR 的最佳截断点为男性 0.51,女性 0.49。总之,WHtR 升高者易发生代谢风险因素群。