Bose Institute, Division of Molecular Medicine, P-1/12, C.I.T. Scheme VII M, Kolkata 700054, India.
Org Biomol Chem. 2019 May 8;17(18):4605-4610. doi: 10.1039/c9ob00670b.
A convenient straightforward method has been developed for 1,2-cis glycosylation and β-mannosylation in excellent yields using glycosyl donors having a 4,6-O-benzylidene acetal together with a p-methoxybenzyl (PMB) or 2-naphthylmethyl (NAP) group at the C-3 position under standard glycosylation conditions.
已开发出一种方便直接的方法,可在标准糖苷化条件下,使用具有 4,6-O-苄叉缩醛和 C-3 位的对甲氧基苄基 (PMB) 或 2-萘甲基 (NAP) 基团的糖基供体,以优异的收率进行 1,2-cis 糖苷化和 β-甘露糖苷化。