Roncero Carlos, Palma-Álvarez Raúl F, Díaz-Morán Sira, Grau-López Lara, Rodríguez-Cintas Laia, Ros-Cucurull Elena, Álvarez Ana I, Casas Miguel, Daigre Constanza
Psychiatry Service, University of Salamanca Health Care Complex Salamanca, (Spain). Instituto de Biomedicina de Salamanca (IBSAL), Universidad de Salamanca, (España).
Departamento de Psiquiatría y Medicina Legal. Instituto de Neurociencias. Universidad Autónoma de Barcelona (España) Sección de Adicciones y Patología Dual, Hospital Universitario Vall Hebron-Agencia de Salud Pública de Barcelona (ASPB). Barcelona (España) Servicio de Psiquiatría, Hospital Universitario Vall Hebron. Universidad Autónoma de Barcelona. CIBERSAM (Spain).
Actas Esp Psiquiatr. 2019 Mar;47(2):37-44. Epub 2019 Mar 1.
Cocaine dependence is a disorder where relapses are frequently presented and many factors are involved. Furthermore, cocaine dependence is associated with poor health-related quality of life (HRQoL) outcomes. This study aims to explore perceived HRQoL as an indicator of drug relapse in cocaine-dependent patients (CDP).
A longitudinal study was carried out in CDP during 23 weeks. A consecutive sampling method was applied, 39 participants composed the initial sample (mean age 35.6 years), only 15 participants completed outpatient follow-up period. CDP were assessed with psychiatric and HRQoL instruments (SCID-I, SCID-II, BDI, STAI scale and SF-36) in different points of the study. The patients were followed up, and cocaine relapses were assessed. The sample was divided according with the relapse (early vs. late relapse). Data were compared and analyzed in order to evaluate whether HRQoL measure could be related to cocaine relapse.
There are differences in perceived HRQoL measures between CDP with/without early relapse, especially in Mental health and Social functioning dimensions (p<0.05). Furthermore, Late/relapse-patients have higher improvement of HRQoL than patients with early relapse.
Perceived HRQoL might predict early relapse and could be a possible predictor tool of potential future relapses. More research in this field is needed.
可卡因依赖是一种经常出现复发且涉及多种因素的疾病。此外，可卡因依赖与健康相关生活质量（HRQoL）较差的结果相关。本研究旨在探讨感知到的HRQoL作为可卡因依赖患者（CDP）药物复发的指标。
对CDP进行了为期23周的纵向研究。采用连续抽样方法，初始样本由39名参与者组成（平均年龄35.6岁），只有15名参与者完成了门诊随访期。在研究的不同时间点，使用精神科和HRQoL工具（SCID-I、SCID-II、BDI、STAI量表和SF-36）对CDP进行评估。对患者进行随访，并评估可卡因复发情况。根据复发情况（早期复发与晚期复发）对样本进行划分。对数据进行比较和分析，以评估HRQoL测量是否与可卡因复发有关。
有/无早期复发的CDP在感知到的HRQoL测量方面存在差异，尤其是在心理健康和社会功能维度（p<0.05）。此外，晚期复发患者的HRQoL改善程度高于早期复发患者。
感知到的HRQoL可能预测早期复发，并且可能是未来潜在复发的一种预测工具。该领域需要更多的研究。
