López Almodóvar Luis F, Lima Cañadas Pedro, Enríquez Puga Andrés, Narváez Mayorga Irene, Buendía Miñano José A, Sánchez Casado Marcelino, Cañas Cañas Alfonso
Department of Cardiac Surgery, Virgen de la Salud Hospital, Toledo, Spain.
Department of Radiology, Virgen de la Salud Hospital, Toledo, Spain.
Aorta (Stamford). 2018 Dec;6(6):125-129. doi: 10.1055/s-0039-1677809. Epub 2019 Apr 24.
Acute Type A aortic dissection (AAAD) is a surgical emergency. In patients with arch and descending aorta involvement (DeBakey Type I), a total aortic arch replacement with frozen elephant trunk (FET) could favor false lumen thrombosis and improve long-term results. The authors hereby present their experience with this technique in a single low-volume center, to assess whether the technique is feasible to treat such disease.
From January 2011 to December 2016, 43 patients with AAAD were operated on in the authors' institution, which carries out 300 to 350 annual procedures. Among these, 12 patients with an intimal tear in the aortic arch and/or proximal descending aorta received a FET procedure (10 males, age 57 years). Concomitant procedures were aortic valve replacement (42%), Bentall (25%), and aortic valve repair (17%).
Cardiopulmonary bypass, cardiac arrest, and circulatory arrest times were 235 ± 43, 171 ± 33, and 75 ± 20 minutes, respectively. The operative mortality was 16.7% ( = 2). Stroke and re-thoracotomy for bleeding occurred in 8% ( = 1) and 8% ( = 1), respectively. There was no spinal cord injury. Follow-up was 36.1 months. During follow-up, no patients died or required a reoperation on the downstream aorta.
Although all patients were operated on in a low-volume center, the results with FET in AAAD are acceptable. Even though this technique demands high technical skills, it is a promising approach in patients with acute aortic dissection.
急性A型主动脉夹层(AAAD)是一种外科急症。对于累及主动脉弓和降主动脉的患者(DeBakey I型),采用带冻结象鼻支架(FET)的全主动脉弓置换术可能有利于假腔血栓形成并改善长期疗效。作者在此介绍他们在一个手术量较少的单一中心应用该技术的经验,以评估该技术治疗此类疾病的可行性。
2011年1月至2016年12月,作者所在机构共开展了43例AAAD手术,该机构每年进行300至350例手术。其中,12例主动脉弓和/或近端降主动脉存在内膜撕裂的患者接受了FET手术(10例男性,年龄57岁)。同期手术包括主动脉瓣置换(42%)、Bentall手术(25%)和主动脉瓣修复(17%)。
体外循环、心脏停搏和循环阻断时间分别为235±43分钟(平均±标准差)、171±33分钟和75±20分钟。手术死亡率为16.7%(n = 2)。卒中发生率为8%(n = 1),因出血再次开胸手术发生率为8%(n = 1)。无脊髓损伤发生。随访时间为36.1个月。随访期间,无患者死亡或需要对降主动脉进行再次手术。
尽管所有患者均在手术量较少的中心接受手术,但AAAD患者采用FET手术的结果是可以接受的。尽管该技术需要较高的技术水平,但对于急性主动脉夹层患者而言,它是一种有前景的治疗方法。