Marek Marta, Horyniecki Maciej, Karpe Jacek, Adamczyk-Sowa Monika, Walecki Jerzy, Kluczewska Ewa
Department of Radiology and Radiodiagnostics, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia, Katowice, Poland.
Department of Neurology, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia, Katowice, Poland.
Pol J Radiol. 2019 Jan 30;84:e80-e85. doi: 10.5114/pjr.2019.82917. eCollection 2019.
Leukoaraiosis (LA), according to the latest classification, is white matter hyperintensity - morphological findings of small blood vessel disease of the brain. This radiological detection of small vessels disease is important because there are no technical possibilities to assess small vessels of the brain using computed tomography (CT) or magnetic resonance imaging (MRI) angiography. Our aim was to analysis the relationship between the extension of leukoaraiosis and severity of ischaemic stroke and brain atrophy.
We retrospectively analysed 77 head CT scans of patients admitted from the emergency room (ER) to the Radiology Department due to suspected stroke. We assessed the severity of leukoaraiosis using the van Swieten scale and brain atrophy by numerous linear measurements.
Statistical analysis failed to demonstrate differences between LA1 and LA2 groups with regard to stroke severity in National Institutes of Health Stroke Scale (NIHSS) ( = 0.2159). There were no differences with regard to clinical severity of stroke between the study groups divided depending on the extent of brain atrophy. There were statistically significant differences with regard to the anterior horn width of the right and left lateral ventricle, posterior horn width of the right and left lateral ventricle, distance between occipital horn of the left lateral ventricle and internal surface of the cranium and third ventricle width depending on the severity of leukoaraiosis.
The results of our studies present an association between the degree leukoaraiosis extension and brain atrophy, but no association between central nervous system tissue atrophy of extent of leukoaraiosis and ischaemic stroke severity.
根据最新分类，脑白质疏松症（LA）是脑小血管疾病的白质高信号——形态学表现。这种小血管疾病的影像学检测很重要，因为利用计算机断层扫描（CT）或磁共振成像（MRI）血管造影技术无法评估脑小血管。我们的目的是分析脑白质疏松症的范围与缺血性卒中和脑萎缩严重程度之间的关系。
我们回顾性分析了77例因疑似卒中从急诊室（ER）收治入放射科患者的头部CT扫描图像。我们使用范·斯维滕量表评估脑白质疏松症的严重程度，并通过多项线性测量评估脑萎缩情况。
统计学分析未能显示LA1组和LA2组在国立卫生研究院卒中量表（NIHSS）评估的卒中严重程度方面存在差异（P = 0.2159）。根据脑萎缩程度划分的研究组之间，卒中的临床严重程度没有差异。根据脑白质疏松症的严重程度，在左右侧脑室前角宽度、左右侧脑室后角宽度、左侧脑室枕角与颅骨内表面之间的距离以及第三脑室宽度方面存在统计学显著差异。
我们的研究结果表明脑白质疏松症的扩展程度与脑萎缩之间存在关联，但脑白质疏松症范围的中枢神经系统组织萎缩与缺血性卒中严重程度之间没有关联。
