Ayık Aydın Hülya, Tuncer Hasan Aykut, Erdoğan Gülgün, Şimşek Tayup
Akdeniz University Faculty of Medicine, Department of Obstetrics and Gynecology, Division of Gynecologic Oncological Surgery, Antalya, Turkey.
Akdeniz University Faculty of Medicine, Department of Pathology, Division of Gynecopathology, Antalya, Turkey.
Turk J Obstet Gynecol. 2019 Mar;16(1):76-79. doi: 10.4274/tjod.galenos.2018.31855. Epub 2019 Mar 27.
Endometrial carcinoma is the most common genital malignancy in women. Endometrioid type is the most common variant of endometrial carcinoma described in literature. Giant cell carcinoma is a rare, and infrequently reported variant of endometrial carcinoma. We present a 75-year-old patient admitted with vaginal bleeding. Transvaginal ultrasound revealed a 26x28 mm hypodense lesion without any adnexal pathology. The patient underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy, and bilateral pelvic, and paraaortic lymph node dissection. The final histopathology report indicated a 3.8x2x9 cm giant cell carcinoma variant of endometrial carcinoma and one positive external iliac lymph node metastasis. Administration of adjuvant carboplatin and paclitaxel chemotherapy was given. As far as we know, this is the fifteenth case reported in the English literature.
子宫内膜癌是女性最常见的生殖系统恶性肿瘤。子宫内膜样型是文献中描述的最常见的子宫内膜癌变体。巨细胞癌是一种罕见的、报道较少的子宫内膜癌变体。我们报告一名75岁因阴道出血入院的患者。经阴道超声显示一个26×28毫米的低密度病变，未发现任何附件病变。患者接受了全腹子宫切除术、双侧输卵管卵巢切除术以及双侧盆腔和腹主动脉旁淋巴结清扫术。最终组织病理学报告显示为一个3.8×2×9厘米的子宫内膜癌巨细胞癌变体，且有一枚髂外淋巴结转移阳性。给予了辅助性卡铂和紫杉醇化疗。据我们所知，这是英文文献中报道的第15例病例。
