Baghdasaryan Lilit
Saint Grigor Lusavorich Medical Center, Gyurjyan 10, Yerevan, Armenia.
Eur Heart J Case Rep. 2018 Apr 10;2(2):yty042. doi: 10.1093/ehjcr/yty042. eCollection 2018 Jun.
Prinzmetal's angina is a very rare disease in children and adolescents. Adults' studies suggest that vasospastic angina is more common in patients with bronchial asthma than in the general population.
A 16-year-old boy with a history of bronchial asthma was admitted to the hospital after successful resuscitation from asystole. On the day of admission, he had a severe left shoulder pain and developed cardiac arrest. He was complaining of left shoulder pain throughout the previous year. During his hospital stay, a second cardiac arrest took place with inferior ST elevation of the electrocardiography recorded after the second successful resuscitation. Diagnostic coronary angiography revealed multiple spasms throughout the coronary bed, which was completely resolved after intracoronary nitroglycerine administration. The patient was diagnosed Printzmetal's vasospasic angina, and the symptoms disappeared gradually with up-titration of a calcium channel blocker and a nitrate.
Previous studies have suggested that the pathogenesis of Prinzmetal's vasospastic angina may be similar to that of bronchial asthma, as we see in the presentation of this young patient.
变异型心绞痛在儿童和青少年中是一种非常罕见的疾病。成人研究表明，血管痉挛性心绞痛在支气管哮喘患者中比在普通人群中更常见。
一名有支气管哮喘病史的16岁男孩在心脏停搏成功复苏后入院。入院当天，他出现严重的左肩疼痛并发生心脏骤停。他在过去一年中一直抱怨左肩疼痛。在他住院期间，第二次成功复苏后记录到心电图下壁ST段抬高，随后发生了第二次心脏骤停。诊断性冠状动脉造影显示整个冠状动脉床多处痉挛，冠状动脉内给予硝酸甘油后痉挛完全缓解。该患者被诊断为变异型血管痉挛性心绞痛，随着钙通道阻滞剂和硝酸盐剂量的增加，症状逐渐消失。
先前的研究表明，变异型血管痉挛性心绞痛的发病机制可能与支气管哮喘相似，正如我们在这位年轻患者的病例中所见。
