College of Animal Science, Anhui Science and Technology University, Bengbu, 233100, People's Republic of China.
Food Funct. 2019 May 22;10(5):2340-2346. doi: 10.1039/c8fo01883a.
Disinhibition of antibiotics promotes the use of probiotics, prebiotics, immune enhancers, and plant extracts. We investigated the effects of stevioside on growth performance, nutrient digestibility, serum parameters, and intestinal microflora in broilers. Eight hundred ninety-six one-day-old male Arbor Acres broiler chicks (average body weight 48.36 ± 0.21 g) were allotted to 1 of 7 experimental treatments. Treatments consisted of: (1) control (basal diet without supplemental stevioside), (2) 100 mg kg-1 supplemental stevioside (S100), (3) 200 mg kg-1 supplemental stevioside (S200), (4) 400 mg kg-1 supplemental stevioside (S400), (5) 800 mg kg-1 supplemental stevioside (S800), (6) 1600 mg kg-1 supplemental stevioside (S1600), and (7) 3200 mg kg-1 supplemental stevioside (S3200). Performance was not affected by stevioside concentration. Dietary stevioside supplementation increased the digestibility of calcium (P < 0.05) and tended to improve phosphorus digestibility (P = 0.0730). There was a linear effect of dietary stevioside on the concentration of serum glucose (P < 0.05). The serum IgG and IgA levels were linearly increased by stevioside supplementation (P < 0.05). In the ileal digesta, the concentration of E. coli decreased with increasing dietary stevioside supplementation (P < 0.05). On the contrary, dietary stevioside supplementation increased the concentration of Bifidobacteria (P < 0.01) and tended to improve the concentration of Lactobacillus (P = 0.0791). In conclusion, our data suggest that stevioside supplementation could improve the calcium and phosphorus digestibility and decrease blood glucose levels of broilers. Additionally, dietary stevioside supplementation significantly increased Bifidobacteria in the cecal digesta, and decreased E. coli.
抑制抗生素的使用会促进益生菌、益生元、免疫增强剂和植物提取物的使用。我们研究了甜菊糖甙对肉鸡生长性能、养分消化率、血清参数和肠道微生物区系的影响。将 896 只 1 日龄雄性 Arbor Acres 肉鸡（平均体重 48.36±0.21g）分为 7 个实验组。处理组包括：（1）对照组（不含甜菊糖甙的基础日粮），（2）100mg/kg 甜菊糖甙（S100），（3）200mg/kg 甜菊糖甙（S200），（4）400mg/kg 甜菊糖甙（S400），（5）800mg/kg 甜菊糖甙（S800），（6）1600mg/kg 甜菊糖甙（S1600）和（7）3200mg/kg 甜菊糖甙（S3200）。甜菊糖甙浓度对生产性能没有影响。日粮中添加甜菊糖甙可提高钙的消化率（P＜0.05），并倾向于提高磷的消化率（P=0.0730）。日粮中添加甜菊糖甙对血清葡萄糖浓度有线性影响（P＜0.05）。血清 IgG 和 IgA 水平随甜菊糖甙的添加而呈线性增加（P＜0.05）。在回肠食糜中，随着日粮中甜菊糖甙添加量的增加，大肠杆菌的浓度降低（P＜0.05）。相反，日粮中添加甜菊糖甙可增加双歧杆菌的浓度（P＜0.01），并倾向于提高乳酸杆菌的浓度（P=0.0791）。综上所述，本研究表明，甜菊糖甙的添加可以提高肉鸡的钙和磷消化率，降低血糖水平。此外，日粮中添加甜菊糖甙可显著增加盲肠食糜中的双歧杆菌，降低大肠杆菌。
