Jansen Mariah R, Kim Kwangwook
Department of Animal Science, Michigan State University, East Lansing, MI 48824, USA.
Animals (Basel). 2024 Oct 19;14(20):3032. doi: 10.3390/ani14203032.
Non-nutritive sweeteners (NNS) have been investigated for their potential to improve feed palatability and growth performance in pigs, although their use in swine production remains limited. This systematic review evaluates the effects of NNS on pigs, drawing from 18 studies published between 1990 and 2024. Following the PRISMA guidelines and using the PICOS framework, a total of 448 papers were initially identified, of which 18 met the inclusion criteria for review. The results are mixed: some studies suggest that NNS like stevioside, sucralose, and neotame may improve performance and reduce diarrhea, while others show limited or no effects. The impact of NNS on gut microbiota is similarly inconsistent, with some sweeteners promoting beneficial bacterial growth, while others show minimal changes in microbial diversity. This review emphasizes the need for more research to clarify the effects of NNS in pigs, particularly the mechanisms behind their influence on growth and gut health. Additionally, further studies are needed to determine optimal dosages and assess the long-term impacts of NNS on pig immune function and overall health. The findings highlight the current gaps in knowledge and suggest that more evidence is needed to understand the role of NNS in swine nutrition.
非营养性甜味剂（NNS）改善猪饲料适口性和生长性能的潜力已得到研究，尽管其在养猪生产中的应用仍然有限。本系统评价从1990年至2024年发表的18项研究中评估了NNS对猪的影响。按照PRISMA指南并使用PICOS框架，最初共识别出448篇论文，其中18篇符合纳入综述的标准。结果不一：一些研究表明，甜菊糖苷、三氯蔗糖和纽甜等NNS可能改善性能并减少腹泻，而其他研究则显示效果有限或无效果。NNS对肠道微生物群的影响同样不一致，一些甜味剂促进有益细菌生长，而其他甜味剂则显示微生物多样性变化极小。本综述强调需要更多研究来阐明NNS对猪的影响，特别是其对生长和肠道健康影响背后的机制。此外，还需要进一步研究以确定最佳剂量，并评估NNS对猪免疫功能和整体健康的长期影响。这些发现凸显了当前知识上的差距，并表明需要更多证据来了解NNS在猪营养中的作用。
