Institute of Child Health and Human Development, National Institutes of Health, University of the Philippines, Manila, Philippines.
PLoS Negl Trop Dis. 2019 Apr 25;13(4):e0007280. doi: 10.1371/journal.pntd.0007280. eCollection 2019 Apr.
Dengue is an important public health problem in the Philippines. We sought to describe the trends in dengue research in the country. We searched four databases and identified published studies on dengue research in the Philippines during the past 60 years. We reviewed 135 eligible studies, of which 33% were descriptive epidemiologic studies or case series, 16% were entomologic or vector control studies, 12% were studies on dengue virology and serologic response, 10% were socio-behavioral and economics studies, 8% were clinical trials, 7% were on burden of disease, 7% were investigations on markers of disease severity, 5% were on dengue diagnostics, and 2% were modeling studies. During the last decade, dengue research in the Philippines has increased and evolved from simple descriptive studies to those with more complex and diverse designs. We identified several key topics where more research would be useful.
登革热是菲律宾的一个重要公共卫生问题。我们旨在描述该国登革热研究的趋势。我们在四个数据库中进行了搜索，确定了过去 60 年来在菲律宾开展的登革热研究的已发表研究。我们回顾了 135 项符合条件的研究，其中 33%为描述性流行病学研究或病例系列，16%为昆虫学或媒介控制研究，12%为登革热病毒学和血清学反应研究，10%为社会行为和经济学研究，8%为临床试验，7%为疾病负担研究，7%为疾病严重程度标志物的研究，5%为登革热诊断研究，2%为建模研究。在过去的十年中，菲律宾的登革热研究有所增加，并从简单的描述性研究发展为更复杂和多样化的设计。我们确定了几个需要进一步研究的关键主题。
