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原发性打鼾和阻塞性睡眠呼吸暂停综合征患儿的鼻腔细胞学检查

Nasal cytology in children with primary snoring and obstructive sleep apnoea syndrome.

作者信息

Nosetti Luana, Piacentini Giorgio, Macchi Alberto, De Bernardi Francesca, Simoncini Daniela, Nicoloso Martina, Agosti Massimo, Zaffanello Marco

机构信息

Division of Pediatrics, "F. Del Ponte" Hospital, University of Insubria, Varese, Italy.

Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy.

出版信息

Int J Pediatr Otorhinolaryngol. 2019 Jul;122:133-137. doi: 10.1016/j.ijporl.2019.04.015. Epub 2019 Apr 17.

Abstract

OBJECTIVE

Rhinitis is an acute or chronic inflammatory condition due to several causes (i.e. infections, allergens). There are controversial results that point out the role of nasal inflammation in primary snoring and obstructive sleep apnoea syndrome (OSAS).

METHODS

The aim of the present investigation is to study the nasal cytology in 58 children aged from 1 to 15 affected by sleep disordered breathing.

RESULTS

Inflammation of the nasal mucous was found in 88% of children. The most frequent problems were infectious rhinitis (36%), followed by non-allergic rhinitis (28%) and allergic rhinitis (21%). Infectious rhinitis was found in 31% of children with primary snoring and 41% with OSAS. Allergic rhinitis was found in 35% of children with primary snoring, and 6% with OSAS. Non-allergic rhinitis was found in 19% of children with primary snoring, and 34% with OSAS. Bacteria was found in 59% of children with OSAS and 46% in children with primary snoring.

CONCLUSION

the most prevalent forms of rhinitis in primary snoring were the allergic rhinitis, and in OSAS group were the non-allergic rhinitis. Bacteria were equally distributed in primary snoring and OSAS children. The nasal cytology provided interesting information that can be used to plan possible treatment strategies.

摘要

目的

鼻炎是一种由多种原因(如感染、过敏原)引起的急性或慢性炎症性疾病。关于鼻腔炎症在原发性打鼾和阻塞性睡眠呼吸暂停综合征(OSAS)中的作用,存在有争议的结果。

方法

本研究的目的是研究58名年龄在1至15岁、患有睡眠呼吸障碍的儿童的鼻腔细胞学。

结果

88%的儿童存在鼻黏膜炎症。最常见的问题是感染性鼻炎(36%),其次是非过敏性鼻炎(28%)和过敏性鼻炎(21%)。在原发性打鼾儿童中,31%患有感染性鼻炎,在OSAS儿童中,41%患有感染性鼻炎。在原发性打鼾儿童中,35%患有过敏性鼻炎,在OSAS儿童中,6%患有过敏性鼻炎。在原发性打鼾儿童中,19%患有非过敏性鼻炎,在OSAS儿童中,34%患有非过敏性鼻炎。在OSAS儿童中,59%检测出细菌,在原发性打鼾儿童中,46%检测出细菌。

结论

原发性打鼾中最常见的鼻炎形式是过敏性鼻炎,而在OSAS组中是非过敏性鼻炎。细菌在原发性打鼾儿童和OSAS儿童中的分布相同。鼻腔细胞学提供了可用于制定可能治疗策略的有趣信息。

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