Bozkurt Bulent, Serife Ugur K, Karamanli Harun, Kucuker Fatma, Ozol Duygu
Department of Respiratory Medicine, Immunology and Allergy Unit, Medical Faculty Turgut Özal University, Ankara, Turkey.
Department of Otorhinolaryngology, Head and Neck Surgery, Medical Faculty Turgut Özal University, Ankara, Turkey.
Sleep Breath. 2017 May;21(2):255-261. doi: 10.1007/s11325-016-1390-4. Epub 2016 Aug 1.
Persistent allergic rhinitis (PAR) is characterized by a chronic, eosinophilic inflammation with nasal congestion and rhinorrhea. Nasal congestion can constitute to sleep-disordered breathing problems that range from simple snoring to obstructive sleep apnea syndrome (OSAS). The purpose of this study was to investigate the effect of PAR on sleep quality and severity of OSAS.
The study included 150 patients presenting with typical symptoms of sleep apnea. Fifty-five patients were diagnosed as PAR (group-1) and were compared with age and body mass index matched 95 individuals (group-2) without any nasal disease. Skin prick tests and polysomnography were performed in all patients.
There were no differences between groups for polysomnographic findings including sleep architecture, arousal and respiratory index, and mean and minimal oxygen saturations. Simple snoring was determined in 41.8 % allergic and 32.6 % non-allergic patients. Mild OSAS was determined in 32.7 % allergic and 29.4 % non-allergic patients. Moderate OSAS was determined in 9 % allergic and 17.8 % non-allergic patients. Severe OSAS was determined in 16.3 % allergic and 20 % non-allergic patients. Their entire Epworth sleepiness scale index was also found similar.
Our data pointed out that in patients with sleep-related breathing disorders symptoms, presence of PAR does not affect polysomnographic parameters compared with other patients without any nasal inflammation. Besides, prevalence of OSAS was similar between groups.
持续性变应性鼻炎(PAR)的特征是慢性嗜酸性粒细胞炎症伴鼻塞和流涕。鼻塞可导致睡眠呼吸障碍问题,范围从单纯打鼾到阻塞性睡眠呼吸暂停综合征(OSAS)。本研究的目的是调查PAR对睡眠质量和OSAS严重程度的影响。
该研究纳入了150例有典型睡眠呼吸暂停症状的患者。55例患者被诊断为PAR(1组),并与年龄和体重指数相匹配的95例无任何鼻部疾病的个体(2组)进行比较。对所有患者进行皮肤点刺试验和多导睡眠图检查。
两组在多导睡眠图检查结果方面无差异,包括睡眠结构、觉醒和呼吸指数以及平均和最低血氧饱和度。41.8%的变应性患者和32.6%的非变应性患者存在单纯打鼾。32.7%的变应性患者和29.4%的非变应性患者存在轻度OSAS。9%的变应性患者和17.8%的非变应性患者存在中度OSAS。16.3%的变应性患者和20%的非变应性患者存在重度OSAS。他们的整个爱泼沃斯思睡量表指数也相似。
我们的数据指出,在有睡眠相关呼吸障碍症状的患者中,与其他无任何鼻部炎症的患者相比,PAR的存在不影响多导睡眠图参数。此外,两组间OSAS的患病率相似。