Bukhari Nedal, Joudeh Amani
Department of Medical Oncology, King Fahad Specialist Hospital, Dammam, Saudi Arabia.
Department of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Am J Case Rep. 2019 Apr 26;20:597-601. doi: 10.12659/AJCR.915334.
BACKGROUND Anaplastic sarcomatoid carcinoma of the pancreas (ASCP) is a rare variant of pancreatic malignancies. It is a high-grade epithelial carcinoma predominated with spindle cells. CASE REPORT We report a case of a 65-year-old patient who presented with early stage, ampullary mass indicating malignancy, and who subsequently underwent pancreatoduodenectomy. Histopathology and immunohistochemistry were confirmatory for anaplastic, grade IV sarcomatoid adenocarcinoma arising from the head of the pancreas. CONCLUSIONS To our knowledge, this is a rare presentation with few cases reported in the literature.
背景 胰腺间变性肉瘤样癌(ASCP)是胰腺恶性肿瘤的一种罕见变体。它是一种以梭形细胞为主的高级别上皮癌。病例报告 我们报告一例65岁患者,其表现为早期壶腹肿物提示恶性,随后接受了胰十二指肠切除术。组织病理学和免疫组化证实为起源于胰头的间变性IV级肉瘤样腺癌。结论 据我们所知,这是一种罕见的表现,文献报道的病例很少。