Orish Verner N, Ofori-Amoah Jones, Amegan-Aho Kokou H, Osei-Yeboah James, Lokpo Sylvester Y, Osisiogu Emmanuel U, Agordoh Percival D, Adzaku Festus K
Department of Microbiology and Immunology, University of Health and Allied Sciences, Ho.
Department of Pharmacology, University of Health and Allied Sciences, Ho.
Open Forum Infect Dis. 2019 Mar 26;6(4):ofz153. doi: 10.1093/ofid/ofz153. eCollection 2019 Apr.
Polyparasitic infection is a possibility in areas where parasites are endemic, especially among children. This study looked at the prevalence of polyparasitic infections among children in the Volta Region of Ghana.
This was a cross-sectional study, among 550 primary school children (aged 6-14 years) in 3 districts in the Volta Region. Questionnaires were administered, and blood, stool, and urine samples were collected. Blood samples were screened for with rapid diagnostic test and microscopy, together with hemoglobin estimation. Stool and urine samples were microscopically examined using wet mount and sedimentation methods to detect intestinal parasites and respectively. Pearson χ test was used to evaluate the association between parasitic infections and socioeconomic variables, and multivariate logistic regression to evaluate paired associations among parasites.
The most prominent infection among the children was (present in 383 children [69.6%]), followed by (57 [10.36%]). There was low prevalence of intestinal protozoa (present in 11 children [2%]), (7 [1.27%]), and hookworm (5 [0.91%]). A total of 62 children had polyparasitic infection, with having significant paired association (both present in 46 children [74.19%]; adjusted odds ratio, 2.45; = .007).
The prevalence of polyparasitic infection was low in this study, and significant coinfection was seen with and .
在寄生虫流行地区，尤其是儿童中，存在多重寄生虫感染的可能性。本研究调查了加纳沃尔特地区儿童多重寄生虫感染的患病率。
这是一项横断面研究，研究对象为沃尔特地区3个区的550名小学生（6至14岁）。发放了问卷，并采集了血液、粪便和尿液样本。血液样本通过快速诊断检测和显微镜检查进行筛查，并进行血红蛋白测定。粪便和尿液样本分别采用湿片法和沉淀法进行显微镜检查，以检测肠道寄生虫和其他寄生虫。采用Pearson χ检验评估寄生虫感染与社会经济变量之间的关联，采用多因素逻辑回归评估寄生虫之间的配对关联。
儿童中最常见的感染是[具体寄生虫名称1]（383名儿童[69.6%]存在该感染），其次是[具体寄生虫名称2]（57名[10.36%]）。肠道原生动物（11名儿童[2%]存在该感染）、[具体寄生虫名称3]（7名[1.27%]）和钩虫（5名[0.91%]）的患病率较低。共有62名儿童存在多重寄生虫感染，其中[具体寄生虫名称1]和[具体寄生虫名称2]存在显著的配对关联（两者均存在于46名儿童中[74.19%]；调整优势比为2.45；P = 0.007）。
本研究中多重寄生虫感染的患病率较低，且[具体寄生虫名称1]和[具体寄生虫名称2]存在显著的合并感染。
