肯尼亚血吸虫病流行地区儿童的多寄生虫感染对贫血和营养不良的影响。
Impact of polyparasitic infections on anemia and undernutrition among Kenyan children living in a Schistosoma haematobium-endemic area.
机构信息
CTID Building, Liverpool School of Tropical Medicine, Liverpool, UK.
出版信息
Am J Trop Med Hyg. 2013 Mar;88(3):433-40. doi: 10.4269/ajtmh.12-0552. Epub 2013 Jan 16.
Abstract
We measured prevalence of Schistosoma haematobium, Wuchereria bancrofti, Plasmodium falciparum, hookworm, and other geohelminths among school-aged children in four endemic villages in Kwale County, Kenya and explored the relationship between multiparasite burden, undernutrition, and anemia. In 2009-2010 surveys, cross-sectional data were obtained for 2,030 children 5-18 years old. Infections were most prevalent for S. haematobium (25-62%), hookworm (11-28%), and falciparum malaria (8-24%). Over one-half of children were anemic, with high rates of acute and chronic malnutrition. Associations with infection status showed significant age and sex differences. For boys, young age, low socioeconomic standing (SES), S. haematobium, and/or malaria infections were associated with greater odds of anemia, wasting, and/or stunting; for girls, heavy S. haematobium infection and age were the significant cofactors for anemia, whereas low SES and older age were linked to stunting. The broad overlap of infection-related causes for anemia and malnutrition and the high frequency of polyparasitic infections suggest that there will be significant advantages to integrated parasite control in this area.
摘要
我们在肯尼亚夸莱县的四个流行地区测量了学龄儿童中埃及血吸虫、班氏丝虫、恶性疟原虫、钩虫和其他土源性蠕虫的流行情况，并探讨了多寄生虫负担、营养不良和贫血之间的关系。在 2009-2010 年的调查中，我们获得了 2030 名 5-18 岁儿童的横断面数据。感染最常见的是埃及血吸虫（25-62%）、钩虫（11-28%）和恶性疟原虫（8-24%）。超过一半的儿童贫血，急性和慢性营养不良的发生率很高。感染状况与贫血、消瘦和/或发育迟缓之间存在显著的年龄和性别差异。对于男孩，年龄较小、社会经济地位较低（SES）、埃及血吸虫和/或疟疾感染与贫血、消瘦和/或发育迟缓的几率增加有关；对于女孩，重度埃及血吸虫感染和年龄是贫血的重要伴随因素，而 SES 较低和年龄较大与发育迟缓有关。贫血和营养不良与感染相关的原因广泛重叠，多寄生虫感染的频率很高，这表明在该地区进行寄生虫综合控制将具有显著优势。
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