Eurich Katrin E, Swisher Elizabeth, Toukatly Mirna, Koch Lisa, Wu Emily S
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Washington, 1959 NE Pacific Street, Box 356460, Seattle, WA 98195, USA.
Department of Pathology, University of Washington, 1959 NE Pacific Street, Box 357470, Seattle, WA 98195, USA.
Gynecol Oncol Rep. 2019 Apr 6;28:124-127. doi: 10.1016/j.gore.2019.04.003. eCollection 2019 May.
•Neoadjuvant chemotherapy (NACT) followed by fertility-sparing surgery is a feasible treatment of metastatic dysgerminoma•As few as two cycles of NACT may result in enough of a tumor response for fertility-sparing surgery to be possible.•Tumor lysis syndrome is a possibility when administering chemotherapy to patients with metastatic dysgerminoma.
•新辅助化疗(NACT)后行保留生育功能手术是转移性无性细胞瘤的一种可行治疗方法。
•NACT仅两个周期就可能产生足够的肿瘤反应,使保留生育功能手术成为可能。
•对转移性无性细胞瘤患者进行化疗时,有可能发生肿瘤溶解综合征。