Slinger Claire, Slinger Richard, Vyas Aashish, Haines Jemma, Fowler Stephen J
Complex Breathlessness Service, Chest Clinic, Lancashire Teaching Hospitals NHS Trust, Royal Preston Hospital Preston United Kingdom.
Division of Health Research, Faculty for Health and Medicine Lancaster University Lancaster United Kingdom.
Laryngoscope Investig Otolaryngol. 2019 Feb 8;4(2):255-258. doi: 10.1002/lio2.229. eCollection 2019 Apr.
To perform a systematic literature review on the use of Heliox with patients with inducible laryngeal obstruction/vocal cord dysfunction to: i) identify current evidence base; and ii) establish the methodological quality of published research.
Articles published up to March 2018 were searched for key words and terms using Cochrane Library, MEDLINE, PubMed, CINAHL, EMBASE and Dynamed. Studies were included if they presented original research into the use of Heliox for vocal cord dysfunction.
Only three studies met the inclusion criteria for review. All reported favorable results for the use of Heliox as an adjunctive therapy for vocal cord dysfunction but none had sufficient methodological quality to support their conclusions.
Despite review articles recommending the use of Heliox in vocal cord dysfunction, there is a lack of good quality research to support this conclusion. There is a need for further research to investigate the effectiveness of Heliox as an adjunctive therapy for vocal cord dysfunction.
对氦氧混合气用于诱导性喉梗阻/声带功能障碍患者进行系统的文献综述，以：i）确定当前的证据基础；ii）评估已发表研究的方法学质量。
使用Cochrane图书馆、MEDLINE、PubMed、CINAHL、EMBASE和Dynamed检索截至2018年3月发表的文章中的关键词和术语。如果研究呈现了关于氦氧混合气用于声带功能障碍的原始研究，则纳入其中。
只有三项研究符合纳入综述的标准。所有研究均报告了氦氧混合气作为声带功能障碍辅助治疗的良好效果，但没有一项研究具有足够的方法学质量来支持其结论。
尽管综述文章推荐在声带功能障碍中使用氦氧混合气，但缺乏高质量的研究来支持这一结论。需要进一步研究以调查氦氧混合气作为声带功能障碍辅助治疗的有效性。
4级。
