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降低四级新生儿重症监护病房的非计划性拔管率。

Reduction in Unintended Extubations in a Level IV Neonatal Intensive Care Unit.

机构信息

Departments of Neonatology.

Virginia Hospital Center, Arlington, Virginia; and.

出版信息

Pediatrics. 2019 May;143(5). doi: 10.1542/peds.2018-0897.

Abstract

OBJECTIVES

Unintended extubations (UEs) lead to significant morbidity in neonates. A quality improvement project was initiated in response to high rates in our level IV NICU. We targeted creating and sustaining UE rates below the published standard of 1 per 100 ventilator days.

METHODS

This project spanned 4 time periods: baseline, epoch 1 (December 2010-May 2012), sustain, and epoch 2 (May 2015-December 2017) by using standard quality improvement methodology. Epoch 1 interventions included real-time analysis of UE events, standardization of taping, patient positioning and movement, accurate event reporting, and change in nomenclature. Epoch 2 interventions included reduction in daily chest radiographs (CXRs) and development of a high-risk tool. Patient and event characteristics were statistically compared across time points.

RESULTS

Of the 612 UE events recorded over 10 years, 249 UEs occurred from May 2011 to 2017 involving 184 unique patients. UE rates decreased by 43% (from 1.75 to 0.99 per 100 ventilator days; epoch 1) and were sustained until a notable spike. Epoch 2 interventions led to a further 31% rate reduction. Single CXR use decreased by half. Median corrected gestational age at the time of an event was 35 weeks (interquartile range: 29-41). Seventy percent of infants experiencing an UE required reintubation, 29% had a previous event, and 9% had a code event.

CONCLUSIONS

A decrease in UE below benchmarks can be achieved and sustained by standardization and mitigation interventions. This decline was also accompanied by a reduction in use of CXRs without increasing UE events.

摘要

目的

非计划性拔管(UEs)可导致新生儿出现严重并发症。由于我们的四级新生儿重症监护病房(NICU)中此类事件发生率较高,因此我们启动了一项质量改进项目。我们的目标是将 UE 发生率控制在低于 1 例/100 通气日的既定标准。

方法

本项目采用标准质量改进方法,跨越了 4 个时间段:基线期、第 1 阶段(2010 年 12 月至 2012 年 5 月)、维持期和第 2 阶段(2015 年 5 月至 2017 年 12 月)。第 1 阶段的干预措施包括实时分析 UE 事件、规范固定方法、患者体位和移动、准确报告事件以及改变命名方式。第 2 阶段的干预措施包括减少每日胸部 X 线检查(CXRs)和开发高危工具。对不同时间段的患者和事件特征进行了统计学比较。

结果

在 10 年期间记录的 612 例 UE 事件中,有 249 例 UE 发生于 2011 年 5 月至 2017 年,涉及 184 例不同的患者。UE 发生率下降了 43%(从 1.75 例/100 通气日降至 0.99 例/100 通气日;第 1 阶段),并一直维持至显著增加。第 2 阶段的干预措施进一步使 UE 发生率降低了 31%。单次 CXR 的使用量减少了一半。事件发生时的校正胎龄中位数为 35 周(四分位间距:29-41)。70%经历 UE 的婴儿需要重新插管,29%有过先前的 UE 事件,9%有过 CODE 事件。

结论

通过标准化和缓解干预措施,可以将 UE 发生率降低至低于基准值并维持该水平。这一下降还伴随着 CXR 使用量的减少,而 UE 事件并未增加。

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