在克隆的功能性淋巴细胞上发现的一种T细胞受体γ/CD3复合物。
A T-cell receptor gamma/CD3 complex found on cloned functional lymphocytes.
作者信息
Borst J, van de Griend R J, van Oostveen J W, Ang S L, Melief C J, Seidman J G, Bolhuis R L
出版信息
Nature. 1987;325(6106):683-8. doi: 10.1038/325683a0.
DOI:10.1038/325683a0
PMID:3102966
Abstract
Cloned blood lymphocytes that do not express the alpha- and beta-chains of the T-cell receptor show MHC-unrestricted cytotoxicity. These cells carry the gamma-protein, disulphide-linked either to another molecule or to itself, and associated with the CD3 complex. These observations may help to solve the mystery posed by the discovery of the gamma gene.
摘要
克隆的血液淋巴细胞不表达T细胞受体的α链和β链，却表现出MHC非限制性细胞毒性。这些细胞携带γ蛋白，通过二硫键与另一个分子相连或自身相连，并与CD3复合物相关联。这些观察结果可能有助于解开γ基因发现所带来的谜团。
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