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科特迪瓦阿比让科科迪大学医院神经科的多神经根病:六年期间的流行病学、临床特征及转归

Polyradiculopathies in the neurology department of the Cocody University Hospital, Abidjan, Ivory Coast: epidemiological and clinical profiles and outcomes over a six-year period.

作者信息

Diallo M, Tanoh A C, Mamadou Z, Diallo L L

机构信息

Centre hospitalier universitaire de Cocody, Abidjan, Côte d'Ivoire.

Centre hospitalier universitaire de Conakry, Guinée.

出版信息

Med Sante Trop. 2019 Feb 1;29(1):76-78. doi: 10.1684/mst.2019.0880.

Abstract

Polyradiculoneuropathies (PRNs) are inflammatory disorders of the peripheral nervous system. They are diffuse in general, sparing neither the proximal portions of the elements of this system, where they predominate, nor the cranial nerves. To describe the epidemiological and diagnostic profiles, as well as the course, of patients with PRN in the Cocody university hospital center (Abidjan) neurology department over the past six years. This retrospective single-center study describes PRN cases and their course during the 6-year period of 2009-2014 in this neurology department. Among 5319 cases seen in the neurology department over the study period, 58 patients met our criteria, i.e., 1.1%. More patients were men: 55.2% for a sex ratio of 1.23. They included 4 cases of ethanol poisoning, 2 cases of undecompensated diabetes, and one reaction to vaccination for yellow fever (AAV). The electroneuromyographic tracing supported a finding of demyelination in 55.1%, axonal loss in 25.9% and both in 19%. PRN is a relatively common pathology that is often overlooked. Etiological investigation was difficult in our setting. Early management can improve the prognosis of this disorder.

摘要

多发性神经根神经病(PRN)是外周神经系统的炎性疾病。它们通常呈弥漫性,既不累及该系统主要分布的近端部分,也不累及颅神经。描述过去六年中阿比让科科迪大学医院中心神经内科PRN患者的流行病学和诊断特征以及病程。这项回顾性单中心研究描述了该神经内科2009年至2014年6年期间的PRN病例及其病程。在研究期间神经内科诊治的5319例病例中,58例符合我们的标准,即占1.1%。男性患者更多:占55.2%,性别比为1.23。其中包括4例乙醇中毒、2例未代偿性糖尿病和1例黄热病疫苗接种反应(AAV)。神经电生理描记显示55.1%存在脱髓鞘表现,25.9%存在轴突丧失,19%两者均有。PRN是一种相对常见但常被忽视的疾病。在我们的环境中病因调查困难。早期管理可改善该疾病的预后。

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