Couitchere L, N'da G, Aholi J M, N'doumy M, Azagoh R, Oulai S
Centre hospitalier universitaire de Treichville, Abidjan, Côte d'Ivoire, Université Felix Houphouet Boigny, 01BP V3 Ab, Abidjan, Côte d'Ivoire.
Centre hospitalier universitaire de Treichville, Abidjan, Côte d'Ivoire.
Med Sante Trop. 2019 Feb 1;29(1):97-101. doi: 10.1684/mst.2019.0875.
Cancer is a major cause of morbidity and mortality in children under the age of 15 years worldwide. To contribute to better knowledge of childhood cancers in Africa. To determine the causes of pediatric cancers and compare them with the results of a previous study and with data available for sub-Saharan Africa. This observational, descriptive study of the data recorded from 2007 to 2015 in the pediatric oncology unit of the University Hospital Center of Treichville in Abidjan analyzes the general and the age- and sex-specific proportions of children under the age of 15 years with neoplasia according to the International Classification of Childhood Cancer, 3rd edition (ICCC.3). This study includes 863 new cases. The sex ratio (M/F) was 1.4, and the mean age 7 years (range: 3 months to 14 years 9 months). The neoplasia rate peaked in the group aged 5-9 years (38.6 %). The most common cancers were: lymphomas (44 %), retinoblastoma (11.7 %), renal tumors (10.1 %), leukemias (6.3 %), and soft tissue sarcomas (5, 9 %). Burkitt lymphoma (85.3 %) and nephroblastoma (90.8 %) were the dominant histological type of lymphoma and renal tumors. This study shows an increase in the annual number of new cases, and an epidemiology close to that reported in other centers in sub-Saharan Africa.
癌症是全球15岁以下儿童发病和死亡的主要原因。为了增进对非洲儿童癌症的了解，确定儿童癌症的病因，并将其与之前一项研究的结果以及撒哈拉以南非洲地区现有的数据进行比较。这项对2007年至2015年在阿比让特雷什维尔大学医院中心儿科肿瘤病房记录的数据进行的观察性、描述性研究，根据《国际儿童癌症分类》第3版（ICCC.3）分析了15岁以下患有肿瘤的儿童的总体以及按年龄和性别划分的比例。该研究包括863例新病例。男女比例（男/女）为1.4，平均年龄为7岁（范围：3个月至14岁9个月）。肿瘤发生率在5至9岁组达到峰值（38.6%）。最常见的癌症类型为：淋巴瘤（44%）、视网膜母细胞瘤（11.7%）、肾肿瘤（10.1%）、白血病（6.3%）和软组织肉瘤（5.9%）。伯基特淋巴瘤（85.3%）和肾母细胞瘤（90.8%）分别是淋巴瘤和肾肿瘤的主要组织学类型。这项研究表明新病例的年度数量有所增加，其流行病学情况与撒哈拉以南非洲其他中心报告的情况相近。
