Kumar Jana A, Agarwal S, Chatterjee S N
Radiat Environ Biophys. 1986;25(4):309-14. doi: 10.1007/BF01214644.
Ultrasonic radiation produced a dose dependent linear increase in lipid peroxidation (MDA formation) in the liposomal membrane. The yield of MDA was significantly inhibited by butylated hydroxytoluene (BHT), the antioxidant, sodium formate, the OH. radical scavenger, and EDTA, the metal ion chelator. Ascorbic acid at low concentration increased the ultrasonic induced MDA formation while high concentrations inhibited lipid peroxidation. A mechanism of ultrasound induced lipid peroxidation is suggested.
超声辐射使脂质体膜中的脂质过氧化（丙二醛形成）呈剂量依赖性线性增加。抗氧化剂丁基羟基甲苯（BHT）、羟基自由基清除剂甲酸钠和金属离子螯合剂乙二胺四乙酸（EDTA）可显著抑制丙二醛的产生。低浓度的抗坏血酸会增加超声诱导的丙二醛形成，而高浓度则会抑制脂质过氧化。本文提出了超声诱导脂质过氧化的机制。
