Barzanji A A, Daniel R C
Res Vet Sci. 1987 Jan;42(1):92-5.
Cardiac output, the proportion of blood passing through arteriovenous shunts and blood flow distribution to various organs were measured and compared in five normocalcaemic and five hypocalcaemic sheep using radioactive microspheres. Hypocalcaemia was induced by infusing sodium EDTA solution intravenously for two hours. There was evidence that microspheres were leached from liver, muscle, adrenal and thyroid tissues during the induction of hypocalcaemia. Hypocalcaemia reduced blood flow rates by more than 58 per cent in all tissues examined except kidney (48 per cent), heart (53 per cent), lung (10 per cent) and bladder (47 per cent) and reduced cardiac output from 3.70 +/- 0.19 (mean +/- SE) litres min-1 to 2.39 +/- 0.14 litres min-1. Approximately 2.2 per cent of cardiac output passed through arteriovenous shunts. This percentage was unaffected by hypocalcaemia.
使用放射性微球对五只血钙正常的绵羊和五只血钙过低的绵羊的心输出量、通过动静脉分流的血液比例以及血液流向各个器官的分布情况进行了测量和比较。通过静脉输注乙二胺四乙酸钠溶液两小时来诱发血钙过低。有证据表明，在诱发血钙过低的过程中，微球从肝脏、肌肉、肾上腺和甲状腺组织中被浸出。除肾脏（48%）、心脏（53%）、肺（10%）和膀胱（47%）外，血钙过低使所有检查组织的血流速率降低超过58%，并使心输出量从3.70±0.19（平均值±标准误）升/分钟降至2.39±0.14升/分钟。约2.2%的心输出量通过动静脉分流。该百分比不受血钙过低的影响。
