Nosdøl G, Waage S
Nord Vet Med. 1981 Jun-Aug;33(6-8):310-26.
Hypocalcaemia was verified in 74.4% of 78 ewes with a clinical diagnosis of hypocalcaemia, the corresponding figure for 99 ewes with an uncertain clinical diagnosis of hypocalcaemia being 21.2%. The tendency to developed hypocalcaemia increased with increasing age. Hypocalcaemic cases were recorded from about 2 months prior to lambing to approx. 11/2 months after lambing, most frequently occurring during the period 2-4 weeks before lambing. The number of lambs in ewes which developed hypocalcaemia was on the average greater than in a group of healthy control ewes. Plasma Ca was higher in ewes with hypocalcaemia which stood firmly as compared with atactic or recumbent cases, and higher in those which showed tetany, were restless or which appeared to be relatively normal, than in those which were dull or comatose. Plasma Mg was lowest in the ewes with tetany. Values for ASAT, ALAT, bilirubin, haemoglobin and packed cell volume were significantly higher in hypocalcaemic ewes than in the healthy control ewes. In the hypocalcaemic ewes, plasma Ca and packed cell volume were negatively correlated, while plasma Ca and plasma P were positively correlated. Approx. 20% of the ewes with hypocalcaemia did not recover. These had higher average plasma Ca and lower average plasma Mg at first treatment than those which recovered. The mortality rate in ewes treated after parturition was higher than in those treated before parturition. Of the hypocalcaemic cases which recovered, approx. 25% required more than one treatment. Ewes which developed hypocalcaemia before lambing and which recovered, lost 22% of their lambs, the main reason probably being premature birth. The differential diagnosis of hypocalcaemia is discussed in the light of clinical and clinico-chemical findings in normocalcaemic ewes to which a diagnosis of clinical or uncertain clinical hypocalcaemia had been given.
在临床诊断为低钙血症的78只母羊中，74.4%被证实存在低钙血症；而在临床诊断不明确的99只母羊中，这一比例为21.2%。发生低钙血症的倾向随年龄增长而增加。低钙血症病例记录从产羔前约2个月至产羔后约1个半月，最常发生在产羔前2 - 4周。发生低钙血症的母羊所产羔羊数量平均多于一组健康对照母羊。与共济失调或卧地的低钙血症母羊相比，站立稳的低钙血症母羊血浆钙水平更高；表现出抽搐、躁动或看似相对正常的低钙血症母羊的血浆钙水平高于呆滞或昏迷的母羊。抽搐的母羊血浆镁水平最低。低钙血症母羊的谷草转氨酶、谷丙转氨酶、胆红素、血红蛋白和红细胞压积值显著高于健康对照母羊。在低钙血症母羊中，血浆钙与红细胞压积呈负相关，而血浆钙与血浆磷呈正相关。约20%的低钙血症母羊未恢复。这些母羊首次治疗时的平均血浆钙水平较高，平均血浆镁水平较低，相比那些恢复的母羊。产后治疗的母羊死亡率高于产前治疗的母羊。在恢复的低钙血症病例中，约25%需要不止一次治疗。产羔前发生低钙血症且恢复的母羊，其羔羊损失了22%，主要原因可能是早产。根据临床诊断为临床或临床诊断不明确的正常血钙母羊的临床和临床化学检查结果，对低钙血症的鉴别诊断进行了讨论。
