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Single nucleotide polymorphisms in angiogenesis-related genes and outcomes from antiangiogenic therapies in renal cell carcinoma: really a step towards personalized oncology, or not at all?

作者信息

Porta Camillo, Cosmai Laura, Rizzo Mimma, Melazzini Mario

机构信息

Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy.

Division of Translational Oncology, I.R.C.C.S. Istituti Clinici Scientifici Maugeri, Pavia, Italy.

出版信息

Ann Transl Med. 2019 Mar;7(Suppl 1):S15. doi: 10.21037/atm.2019.01.51.

DOI:10.21037/atm.2019.01.51
PMID:31032296
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6462585/
Abstract
摘要

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Clin Cancer Res. 2019 Feb 15;25(4):1165-1173. doi: 10.1158/1078-0432.CCR-18-1724. Epub 2018 Nov 6.
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Ann Transl Med. 2018 Apr;6(8):157. doi: 10.21037/atm.2018.04.05.
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Ann Transl Med. 2017 May;5(10):208. doi: 10.21037/atm.2017.04.04.
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Population Modeling Integrating Pharmacokinetics, Pharmacodynamics, Pharmacogenetics, and Clinical Outcome in Patients With Sunitinib-Treated Cancer.在接受舒尼替尼治疗的癌症患者中,整合药代动力学、药效学、药物遗传学和临床结局的群体建模。
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