Garcia-Bengochea F, Friedman W A
Surg Neurol. 1987 Apr;27(4):361-4. doi: 10.1016/0090-3019(87)90012-7.
Searching the medical literature for persistent memory loss following section of the anterior fornix in humans, 13 reports were found and reviewed. They comprised 193 patients of whom 180 underwent fornicotomy for the treatment of epilepsy, and 13 underwent removal of third ventricle colloid cysts. Only 4 were reported to have persistent memory loss postoperatively and they were in the colloid cyst group. Within the limitations inherent to this type of analysis and to the problems of detection and quantification of memory deficits, the reviewed material supports the hypothesis that with anterior fornix section we are only interfering with a part of the structural system subserving memory and that the tumor, the surgical trauma, or other destructive pathology, or a combination of factors including the variability of neural localization, may cause persistent memory loss by additional damage to structures other than the anterior fornix. Language and geographical barriers may explain the apparent failure in communication between early investigators.
在医学文献中搜索人类前穹窿切断术后持续性记忆丧失的相关内容时，共找到并审阅了13份报告。这些报告涉及193例患者，其中180例接受了穹窿切开术以治疗癫痫，13例接受了第三脑室胶样囊肿切除术。据报道，只有4例术后出现持续性记忆丧失，且均在胶样囊肿组。鉴于此类分析固有的局限性以及记忆缺陷检测和量化方面的问题，所审阅的资料支持以下假设：切断前穹窿仅干扰了部分参与记忆的结构系统，而肿瘤、手术创伤或其他破坏性病变，或包括神经定位变异性在内的多种因素共同作用，可能通过对前穹窿以外结构的额外损伤导致持续性记忆丧失。语言和地理障碍或许可以解释早期研究者之间明显的沟通不畅。
