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肠内给予葡萄糖后围手术期的吸收与激素反应

[Resorption and hormonal reaction in the perioperative phase following enteral administration of glucose].

作者信息

Butters M, Bittner R, Scheunert T, Schusdziarra V, Beger H G

出版信息

Z Gastroenterol. 1986 Dec;24(12):732-7.

PMID:3103341
Abstract

It was the aim of this study to find out whether a postoperative enteral nutrition with glucose is possible. Therefore, an intraduodenal glucose load (15 g/7.5 min.; 20% solution) was applied in 14 patients with normal weight and no metabolic disorders before and on 4 consecutive days after a medium severe abdominal operation. The results show that the resorption of the enterally applied glucose is reduced only on the first postoperative day. After the peak values have been reached, the decrease of glucose from the blood is delayed up to the second postoperative day, although during the whole testing period the insulin secretion--calculated according to the insulinogenic index - corresponds to the glucose stimulation. Thus, an early postoperative enteral nutrition with glucose seems to be possible, but the reduced absorption over a short period has to be taken into consideration.

摘要

本研究的目的是确定术后给予葡萄糖进行肠内营养是否可行。因此,对14例体重正常且无代谢紊乱的患者在中度严重腹部手术后,于术前及术后连续4天给予十二指肠内葡萄糖负荷(15g/7.5分钟;20%溶液)。结果显示,肠内给予的葡萄糖吸收仅在术后第一天降低。在达到峰值后,血糖中葡萄糖的下降在术后第二天之前都会延迟,尽管在整个测试期间,根据胰岛素生成指数计算的胰岛素分泌与葡萄糖刺激相对应。因此,术后早期给予葡萄糖进行肠内营养似乎是可行的,但必须考虑短期内吸收减少的情况。

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