稳定早产儿的体温：“包裹”保暖！——一项随机对照试验。

Euthermia in Stable Preterm Babies: 'Cocooning' for Warmth! - A Randomized Controlled Trial.

机构信息

Department of Neonatology, Kerala Institute of Medical Sciences, Trivandrum 695029, Kerala.

出版信息

J Trop Pediatr. 2020 Feb 1;66(1):15-23. doi: 10.1093/tropej/fmz025.

Abstract

Very preterm babies, after their initial need for rigorous supports, remain in intensive care units for maintaining euthermia. We compared proportion of 'hypothermia OR hyperthermia episodes(HHE)'; physiological instability events; and weight gain in stable preterm babies between 29 and 32 weeks nursed in Cocoon warmer (CW) vs. servo-controlled Radiant warmer(RW) in the intervals between kangaroo mother care. Sixty-six babies were randomized to CW and 59 to RW; number of temperature recordings over 24 h in CW were 1417 and 1271 in RW. HHE were comparable in RW (4.64%) and CW (5.15%); RR 1.1(0.79-1.55), p = 0.6. The combined incidence of physiological instability events was less in CW than RW [(RR 0.49 (0.25-0.97), p = 0.06]. Mean weight gain was similar, being 13.4 ± 6.1 g/day in CW and 12.8 ± 4.9 g/day in RW (p = 0.55). CW was comparable to RW in thermoregulation of hospitalized stable preterm babies.

摘要

极早产儿在最初需要严格的支持后，仍需要在重症监护病房中维持体温正常。我们比较了在袋鼠式护理间隔期间，使用 Cocoon 保温箱（CW）和 servo-controlled Radiant 保温箱（RW）护理的 29 至 32 周龄稳定早产儿的“低体温或高体温发作（HHE）”比例、生理不稳定事件和体重增加。66 名婴儿随机分配到 CW 组，59 名婴儿分配到 RW 组；CW 组的 24 小时内体温记录次数为 1417 次，RW 组为 1271 次。RW 组（4.64%）和 CW 组（5.15%）的 HHE 发生率相当；RR 1.1（0.79-1.55），p=0.6。CW 组的生理不稳定事件总发生率低于 RW 组[RR 0.49（0.25-0.97），p=0.04]。平均体重增加也相似，CW 组为 13.4±6.1 g/天，RW 组为 12.8±4.9 g/天（p=0.55）。CW 在稳定早产儿的住院体温调节方面与 RW 相当。