a Department of Urogynaecology , King's College Hospital , London , UK.
Climacteric. 2019 Jun;22(3):250-256. doi: 10.1080/13697137.2018.1552254.
Overactive bladder (OAB) is a common and distressing condition which is known to increase with age and has a significant effect on quality of life. Whilst OAB is a symptomatic diagnosis, many patients will require basic investigations prior to initiating the appropriate management. This article will review the initial clinical assessment and management of women complaining of OAB including conservative measures and drug therapy, and will also focus on the role of estrogen. In addition, the management of refractory OAB will also be discussed including more invasive strategies such as neuromodulation, Botulinum Toxin, and reconstructive surgery.
膀胱过度活动症（OAB）是一种常见且令人痛苦的疾病，随着年龄的增长而增加，对生活质量有重大影响。虽然 OAB 是一种症状性诊断，但许多患者在开始适当的治疗之前需要进行基本的检查。本文将回顾女性抱怨 OAB 的初始临床评估和管理，包括保守措施和药物治疗，并将重点放在雌激素的作用上。此外，还将讨论难治性 OAB 的管理，包括更具侵入性的策略，如神经调节、肉毒杆菌毒素和重建手术。
