Department of Urogynaecology, Kings College Hospital, London, UK.
Maturitas. 2012 Feb;71(2):188-93. doi: 10.1016/j.maturitas.2011.11.016. Epub 2011 Dec 23.
Overactive bladder (OAB) is a clinical syndrome describing the symptom complex of urgency, with or without urgency incontinence and is usually associated with frequency and nocturia. Whilst a number of women may be managed based on a clinical diagnosis alone urodynamic studies may be useful in those women with complex or refractory symptoms. In the first instance all women will benefit from a conservative approach using bladder retraining although a number will require antimuscarinic therapy. For those women with persistent symptoms following medical therapy alternative treatment modalities such as intravesical Botulinum Toxin, neuromodulation or reconstructive surgery may be considered. This review, whilst giving an overview of the syndrome, will focus on a practical clinical approach to managing women with symptoms of overactive bladder (OAB).
膀胱过度活动症(OAB)是一种临床综合征,描述了尿急症状,伴有或不伴有急迫性尿失禁,通常伴有尿频和夜尿。尽管许多女性可能仅根据临床诊断进行管理,但对于那些症状复杂或难治的女性,尿动力学研究可能会有所帮助。在最初阶段,所有女性都将受益于使用膀胱训练的保守方法,尽管许多女性需要抗毒蕈碱治疗。对于那些在药物治疗后仍有持续症状的女性,可考虑替代治疗方法,如膀胱内肉毒杆菌毒素、神经调节或重建手术。本综述概述了该综合征,重点介绍了管理膀胱过度活动症(OAB)症状女性的实用临床方法。