Wu Hui, Huang Jie
Department of Anesthesiology, Hanzhong Central Hospital, Hanzhong, Shaanxi, China.
Department of Anesthesiology, Hanzhong Central Hospital, Hanzhong, Shaanxi, China
BMJ Open. 2025 May 28;15(5):e100085. doi: 10.1136/bmjopen-2025-100085.
Emerging studies have compared the analgesic effects of quadratus lumborum block versus caudal block in paediatric surgeries, but the results remain controversial. This protocol of a systematic review and meta-analysis aims to determine whether quadratus lumborum block is better than caudal block for postoperative analgesia in paediatric surgeries.
PubMed, EMBASE, the Cochrane Library and Web of Science will be systematically searched from inception to 30 May 2025. The language will be restricted to English. Randomised controlled trials that compared the efficacy and safety of quadratus lumborum block and caudal block in paediatric patients will be included. The duration of analgesia, defined as the time to first analgesic request, will be the primary outcome. The secondary outcomes will include total opioid consumption over the first 24 hours postoperatively, pain scores at rest and during movement, and the incidence of side effects. RevMan V.5.4 software will be used for the statistical analysis. The Grading of Recommendations Assessment, Development and Evaluation approach will be applied to assess the evidence quality.
Ethical approval is not applicable. The results will be publicly published when completed.
CRD42025637094.
新兴研究已比较了小儿手术中腰方肌阻滞与骶管阻滞的镇痛效果，但结果仍存在争议。本系统评价和荟萃分析方案旨在确定小儿手术中腰方肌阻滞在术后镇痛方面是否优于骶管阻滞。
将对PubMed、EMBASE、Cochrane图书馆和Web of Science从建库至2025年5月30日进行系统检索。语言将限制为英语。纳入比较小儿患者腰方肌阻滞和骶管阻滞疗效及安全性的随机对照试验。镇痛持续时间定义为首次要求镇痛的时间，将作为主要结局。次要结局将包括术后24小时内的总阿片类药物消耗量、静息和活动时的疼痛评分以及副作用发生率。将使用RevMan V.5.4软件进行统计分析。将应用推荐分级评估、制定和评价方法来评估证据质量。
无需伦理批准。结果完成后将公开发表。
PROSPERO注册号：CRD42025637094。
