Sugandhavesa Nantawit, Sawaddiruk Passakorn, Bunmaprasert Torphong, Pattanakuhar Sintip, Chattipakorn Siriporn C, Chattipakorn Nipon
Department of Orthopedics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Department of Anesthesiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Am J Case Rep. 2019 Apr 30;20:628-630. doi: 10.12659/AJCR.915282.
BACKGROUND Hiccups induced by steroids administration is not common. Although it is not life-threatening and is always recognized as a transient and minor complication, it can be severely uncomfortable and significantly diminished patient quality of life. In this case report, persistent hiccups were observed in 2 middle-aged Thai men receiving low-dose intravenous dexamethasone. This case report highlights the awareness of severe dexamethasone-induced hiccups. CASE REPORT A 49-year-old man and a 38-year-old man were admitted to our hospital and received IV dexamethasone. The hiccups started after each patient received a single dose of dexamethasone. The frequency and severity of their hiccups increased over time during dexamethasone treatment. Hiccups still continued to occur despite the discontinuation of dexamethasone and lasted for 72 h after drug termination. CONCLUSIONS Dexamethasone can cause persistent hiccups. Although hiccups are not life-threatening, it should not be neglected since it can be severely uncomfortable and significantly diminish patient quality of life. Termination of dexamethasone can gradually relieve hiccups. Dexamethasone should be used cautiously and clinicians must be aware of this undesirable effect.
使用类固醇药物引起的打嗝并不常见。虽然它不会危及生命，且一直被认为是一种短暂的轻微并发症，但它可能会让人极度不适，并显著降低患者的生活质量。在本病例报告中，两名接受低剂量静脉注射地塞米松的泰国中年男性出现了持续性打嗝。本病例报告强调了对严重的地塞米松诱导性打嗝的认识。病例报告：一名49岁男性和一名38岁男性入住我院并接受静脉注射地塞米松治疗。打嗝在每名患者接受单剂量地塞米松后开始出现。在地塞米松治疗期间，他们打嗝的频率和严重程度随时间增加。尽管停用了地塞米松，打嗝仍持续出现，且在停药后持续了72小时。结论：地塞米松可导致持续性打嗝。虽然打嗝不会危及生命，但不应被忽视，因为它可能会让人极度不适，并显著降低患者的生活质量。停用 地塞米松可逐渐缓解打嗝。应谨慎使用地塞米松，临床医生必须意识到这种不良影响。
