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阿育吠陀草药导致的肝硬化。

Ayurveda Herbal Medicine-induced Liver Cirrhosis.

作者信息

Philips Cyriac A, Augustine Philip, Paramaguru Rajaguru, Ahamed Rizwan, Padsalgi Guruprasad

机构信息

Gastroenterology, Cochin Gastroenterology Group, Kochi, IND.

Pathology, PVS Memorial Hospital, Ernakulam, IND.

出版信息

Cureus. 2019 Feb 22;11(2):e4122. doi: 10.7759/cureus.4122.

DOI:10.7759/cureus.4122
PMID:31037236
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6478493/
Abstract

We present the rare case of a young male with sinusoidal obstruction syndrome due to Ayurvedic herbal medicine which he took for management of bilateral leg swelling associated with protein-losing enteropathy due to intestinal lymphangiectasia. The patient developed progressive sinusoidal fibrosis leading to cirrhosis on long term follow-up. In a diagnosis that took three years to conclude, we showcase serial liver biopsies that reveal the rare disease progression. Complementary and alternative medicine use among apparently healthy population is a potentially modifiable risk factor for liver diseases, in the presence of adequate public health education from concerned authorities.

摘要

我们报告了一例罕见病例,一名年轻男性因服用阿育吠陀草药而患上窦性阻塞综合征,他服用该草药是为了治疗因肠道淋巴管扩张症导致的蛋白丢失性肠病伴双侧腿部肿胀。在长期随访中,患者出现了进行性窦性纤维化,最终发展为肝硬化。在一个耗时三年才得出诊断结果的病例中,我们展示了系列肝脏活检结果,这些结果揭示了这种罕见疾病的进展情况。在相关当局进行充分的公共卫生教育的情况下,在看似健康的人群中使用补充和替代医学是肝脏疾病一个潜在的可改变的危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06e9/6478493/4296178d2a8a/cureus-0011-00000004122-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06e9/6478493/8e9e573014d4/cureus-0011-00000004122-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06e9/6478493/93e7b34199c8/cureus-0011-00000004122-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06e9/6478493/b779be731140/cureus-0011-00000004122-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06e9/6478493/4296178d2a8a/cureus-0011-00000004122-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06e9/6478493/8e9e573014d4/cureus-0011-00000004122-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06e9/6478493/93e7b34199c8/cureus-0011-00000004122-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06e9/6478493/b779be731140/cureus-0011-00000004122-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06e9/6478493/4296178d2a8a/cureus-0011-00000004122-i04.jpg

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引用本文的文献

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本文引用的文献

1
Sinusoidal obstruction syndrome.窦状隙阻塞综合征。
Clin Res Hepatol Gastroenterol. 2016 Sep;40(4):378-85. doi: 10.1016/j.clinre.2016.01.006. Epub 2016 Mar 30.
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Mainstreaming of Ayurveda, Yoga, Naturopathy, Unani, Siddha, and Homeopathy with the health care delivery system in India.将阿育吠陀、瑜伽、顺势疗法、尤纳尼、悉达和顺势疗法纳入印度的医疗保健提供系统。
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Sinusoidal obstruction syndrome/veno-occlusive disease: current situation and perspectives-a position statement from the European Society for Blood and Marrow Transplantation (EBMT).
窦性阻塞综合征/静脉闭塞性疾病:现状与展望——欧洲血液与骨髓移植学会(EBMT)的立场声明
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Sinusoidal obstruction syndrome (hepatic veno-occlusive disease).窦性阻塞综合征(肝静脉闭塞病)
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Liver fibrosis in primary intestinal lymphangiectasia: An undervalued topic.原发性肠淋巴管扩张症中的肝纤维化:一个被低估的话题。
World J Hepatol. 2014 Sep 27;6(9):685-7. doi: 10.4254/wjh.v6.i9.685.
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Hepatic sinusoidal obstruction syndrome caused by herbal medicine: CT and MRI features.草药相关性肝窦阻塞综合征:CT 和 MRI 特征。
Korean J Radiol. 2014 Mar-Apr;15(2):218-25. doi: 10.3348/kjr.2014.15.2.218. Epub 2014 Mar 7.