Licinio Raffaele, Principi Mariabeatrice, Ierardi Enzo, Di Leo Alfredo
Raffaele Licinio, Mariabeatrice Principi, Enzo Ierardi, Alfredo Di Leo, Gastroenterology Unit, Department of Emergency and Organ Transplantation, University of Bari, Cesare, 70124 Bari, Italy.
World J Hepatol. 2014 Sep 27;6(9):685-7. doi: 10.4254/wjh.v6.i9.685.
The relationship between primary intestinal lymphangiectasia (PIL) and liver fibrosis is an emerging topic with many obscure aspects due to the rarity of the disorder. A recent paper reported that a six-month low-fat diet improved liver fibrosis. We report the case of a 17-year-old girl affected by PIL whose hepatic fibrosis progressively worsened within one year, despite dietetic support. This and the previous case report describe extraordinary events, which do not allow clear-cut clinical aspects to be established. Nevertheless, both cases suggest that in patients with PIL, it is necessary to closely monitor liver morphology with in-depth investigations including not only ultrasonography, but also elastography.
由于原发性肠淋巴管扩张症（PIL）较为罕见，其与肝纤维化之间的关系是一个新出现且诸多方面尚不明朗的课题。最近一篇论文报道，为期六个月的低脂饮食可改善肝纤维化。我们报告一例17岁患PIL的女孩，尽管给予饮食支持，但其肝纤维化在一年内仍逐渐加重。本病例及之前的病例报告描述了一些特殊情况，无法明确确立清晰的临床特征。然而，两例病例均提示，对于PIL患者，有必要通过包括超声检查及弹性成像等深入检查密切监测肝脏形态。
