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痴呆症患者健康与安全能力的神经心理学预测指标

Neuropsychological predictors of health and safety abilities in dementia.

作者信息

Emmert Natalie A, Schwarz Lauren R, Vander Wal Jillon S, Gfeller Jeffrey D

机构信息

Saint Louis University, St. Louis, Missouri, USA.

出版信息

Appl Neuropsychol Adult. 2021 Jan-Feb;28(1):94-106. doi: 10.1080/23279095.2019.1599893. Epub 2019 Apr 30.

DOI:10.1080/23279095.2019.1599893
PMID:31039631
Abstract

The Independent Living Scales Health and Safety (ILS HS) scale is commonly used by neuropsychologists when evaluating older adults' instrumental activities of daily living (IADLs). However, there is a minimal amount of research on its use in dementia populations and, specifically, its relationship to other neuropsychological measures. The present study investigated relationships between the ILS HS scale and measures of cognition and depression. The study utilized archival data from a sample ( = 142) of older adults (mean age = 77.85) diagnosed with dementia, who were evaluated at Saint Louis University Medical Center and administered the ILS HS scale as part of a larger clinical neuropsychological evaluation. Multiple regression analyses demonstrated that up to 37% of the variance in ILS HS performance was accounted for by demographic variables, premorbid intelligence, and cognitive functioning (e.g., global cognition, delayed verbal recall, and executive functioning), and regression models demonstrated medium to large effect sizes. Depression and self- or informant-reported IADLs were unrelated to the ILS HS scale. Results suggest that older adults' ability to function in health and safety-related situations requires a range of cognitive abilities. Performance on these measures may help guide clinical decision making regarding independent living and treatment planning.

摘要

独立生活量表健康与安全(ILS HS)量表在神经心理学家评估老年人的工具性日常生活活动(IADL)时常用。然而,关于其在痴呆症人群中的使用,特别是其与其他神经心理学测量方法的关系,研究极少。本研究调查了ILS HS量表与认知和抑郁测量方法之间的关系。该研究利用了来自圣路易斯大学医学中心接受评估的142名被诊断患有痴呆症的老年人(平均年龄 = 77.85岁)样本的存档数据,他们作为更大规模临床神经心理学评估的一部分接受了ILS HS量表测试。多元回归分析表明,ILS HS表现中高达37%的方差可由人口统计学变量、病前智力和认知功能(如整体认知、延迟言语回忆和执行功能)解释,回归模型显示出中等至较大的效应量。抑郁以及自我报告或他人报告的IADL与ILS HS量表无关。结果表明,老年人在与健康和安全相关情况下的功能能力需要一系列认知能力。这些测量方法的表现可能有助于指导关于独立生活和治疗计划的临床决策。

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