Faculty of Health, Education and Life Sciences, Birmingham City University, City South Campus, Westbourne Road, Edgbaston, Birmingham, B15 3TN, UK.
EGA Institute for Women's Health, University College London, NIHR University College London Hospitals Biomedical Research Centre, Maple House, 149 Tottenham Court Road, London, W1T 7DN, UK.
BMC Pregnancy Childbirth. 2019 Apr 30;19(1):144. doi: 10.1186/s12884-019-2277-8.
The EVERREST Prospective Study is a multicentre observational cohort study of pregnancies affected by severe early-onset fetal growth restriction. The study recruits women with singleton pregnancies where the estimated fetal weight is less than the 3rd centile and below 600 g, between 20 + 0 and 26 + 6 weeks of pregnancy, in the absence of a known chromosomal, structural or infective cause.
The reported study was retrospective descriptive qualitative interview study of women who had participated in the EVERREST Prospective Study. The aim of this study was to explore the experiences and perceptions of pregnant women taking part in research during a pregnancy affected by severe early-onset fetal growth restriction. Audio-recorded semi-structured telephone interviews were conducted with a purposive sample of 12 women, at least 1 year after delivery of their baby. Two of these pregnancies had ended in stillbirth and one in neonatal death, reflecting the outcomes seen in the EVERREST Prospective Study. Participants gave informed consent, were 16 years or older and were interviewed in English. A topic guide was used to ensure a consistent approach. Questions focused on pregnancy experiences, involvement with the EVERREST study and potential involvement in future research. Recordings were transcribed verbatim for thematic analysis using NVivo10.
Four broad themes were identified; 'before joining the EVERREST Prospective Study', 'participating in research', 'information and support' and 'looking back and looking forwards'. Each broad theme incorporated several subthemes. All participants recalled their reaction to being told their baby was smaller than expected. The way this news was given had a lasting impact. A range of benefits of participation in the EVERREST Prospective Study were described and the participants were positive about the way it was conducted. As a consequence, they were receptive to participating in future research. However, the findings suggest that research teams should be sensitive when approaching families at a difficult time or when they are already participating in other research.
This study highlights the willingness of pregnant women to participate in research and identifies strategies for researchers to engage participants.
EVERREST 前瞻性研究是一项多中心观察性队列研究，研究对象为患有严重早期胎儿生长受限的妊娠。该研究招募了估计胎儿体重低于第 3 百分位且低于 600 克、妊娠 20+0 至 26+6 周且无已知染色体、结构或感染原因的单胎妊娠女性。
本报告研究是对参加 EVERREST 前瞻性研究的女性进行的回顾性描述性定性访谈研究。本研究的目的是探讨在严重早期胎儿生长受限的妊娠中参与研究的孕妇的经历和感受。通过有目的的抽样，对至少在分娩后 1 年的 12 名女性进行了音频记录的半结构式电话访谈。其中 2 例妊娠以死胎告终，1 例以新生儿死亡告终，反映了 EVERREST 前瞻性研究中的结局。参与者在知情同意的情况下，年龄在 16 岁或以上，并以英语接受访谈。使用主题指南确保采用一致的方法。问题集中在妊娠经历、参与 EVERREST 研究以及潜在的未来研究参与。使用 NVivo10 对记录进行逐字转录，进行主题分析。
确定了四个广泛的主题；“加入 EVERREST 前瞻性研究之前”、“参与研究”、“信息和支持”和“回顾过去和展望未来”。每个广泛的主题都包含几个子主题。所有参与者都回忆起他们得知自己的婴儿比预期小的反应。告知这一消息的方式产生了持久的影响。描述了参与 EVERREST 前瞻性研究的一系列好处，参与者对研究的进行方式持积极态度。因此，他们愿意参与未来的研究。然而，研究结果表明，研究团队在困难时期或当他们已经参与其他研究时，应该对家庭保持敏感。
这项研究强调了孕妇参与研究的意愿，并确定了研究人员吸引参与者的策略。
