Basham C Andrew, Karim Mohammad Ehsanul
a School of Population and Public Health , University of British Columbia , Vancouver , Canada.
b TB Services , British Columbia Centre for Disease Control , Vancouver , Canada.
Int J Circumpolar Health. 2019 Dec;78(1):1607703. doi: 10.1080/22423982.2019.1607703.
Rapid social, economic, and environmental changes in the northern territories of Canada have raised concerns about potentially increasing levels of chronic disease. This concern prompted us to compare multimorbidity prevalence in Canada between the territories and provinces. We analyzed Canadian Community Health Survey data for 2013/14. We defined multimorbidity, the outcome, as having 3 or more chronic conditions and used survey-weighted multivariable logistic regression for comparisons between territories and provinces. We found a prevalence of multimorbidity in Canada of 14.0% (95% CI: 13.6, 14.3). We could not find significant difference in multimorbidity prevalence between the territories and provinces of Canada overall; however, the territories tended to have lower prevalence estimates than provinces for multimorbidity (adj-OR = 0.88; 95% CI: 0.74-1.04). Sensitivity analyses from propensity score analyses had similar conclusions. Effect modification analyses identified lower multimorbidity in territories versus provinces among households without a post-secondary graduate (adj-OR = 0.46; 95% CI: 0.34-0.61 for northern residence), males (adj-OR = 0.71; 95% CI: 0.54-0.93), and ages 12-29 years (adj-OR = 0.63; 95% CI: 0.39-0.99). Caution is needed in interpreting the results in light of representativeness of CCHS in northern populations of Canada.
加拿大北部地区快速的社会、经济和环境变化引发了人们对慢性病潜在增加水平的担忧。这种担忧促使我们比较加拿大各地区和省份的多重疾病患病率。我们分析了2013/14年加拿大社区健康调查数据。我们将多重疾病(即研究结果)定义为患有3种或更多慢性病,并使用调查加权多变量逻辑回归来比较各地区和省份。我们发现加拿大的多重疾病患病率为14.0%(95%置信区间:13.6,14.3)。总体而言,我们未发现加拿大各地区和省份之间的多重疾病患病率存在显著差异;然而,各地区的多重疾病患病率估计往往低于省份(调整后比值比=0.88;95%置信区间:0.74 - 1.04)。倾向得分分析的敏感性分析得出了类似结论。效应修正分析发现,在没有高等教育学历的家庭、男性以及12至29岁人群中,各地区的多重疾病患病率低于省份(北方居民的调整后比值比=0.46;95%置信区间:0.34 - 0.61),男性(调整后比值比=0.71;95%置信区间:0.54 - 0.93),以及12至29岁年龄组(调整后比值比=0.63;95%置信区间:0.39 - 0.99)。鉴于加拿大社区健康调查在加拿大北部人群中的代表性,在解释结果时需要谨慎。