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多重疾病患病率的社会差异——一项基于登记处的人群研究。

Social disparities in the prevalence of multimorbidity - A register-based population study.

作者信息

Schiøtz Michaela L, Stockmarr Anders, Høst Dorte, Glümer Charlotte, Frølich Anne

机构信息

Intersectoral Research Unit for Health Services, The Danish Capital Region, Bispebjerg Bakke 23, Building 20D, 2nd Floor, DK, -2400, Copenhagen, NV, Denmark.

Research Unit for Chronic Conditions, Bispebjerg University Hospital, Bispebjerg Bakke 23, Building 20D, 2nd Floor, DK, -2400, Copenhagen, NV, Denmark.

出版信息

BMC Public Health. 2017 May 10;17(1):422. doi: 10.1186/s12889-017-4314-8.

Abstract

BACKGROUND

Prevalences of multimorbidity vary between European studies and several methods and definitions are used. In this study we examine the prevalence of multimorbidity in relation to age, gender and educational attainment and the association between physical and mental health conditions and educational attainment in a Danish population.

METHODS

A cross-sectional design was used to study the prevalence of multimorbidity, defined as two or more chronic conditions, and of comorbid physical and mental health conditions across age groups and educational attainment levels among 1,397,173 individuals aged 16 years and older who lived in the Capital Region of Denmark on January 1st, 2012. After calculating prevalence, odds ratios for multimorbidity and mental health conditions were derived from logistic regression on gender, age, age squared, education and number of physical conditions (only for odds ratios for mental health conditions). Odds ratios for having multimorbidity and mental health conditions for each variable were adjusted for all other variables.

RESULTS

Multimorbidity prevalence was 21.6%. Half of the population aged 65 and above had multimorbidity, and prevalence was inversely related to educational attainment: 26.9% (95% CI, 26.8-26.9) among those with lower secondary education versus 13.5% (95% CI, 13.5-13.6) among people with postgraduate education. Adjusted odds ratios for multimorbidity were 0.50 (95% CI, 0.49-0.51) for people with postgraduate education, compared to people with lower secondary education. Among all population members, 4.9% (95% CI, 4.9-4.9) had both a physical and a mental health condition, a proportion that increased to 22.6% of people with multimorbidity. Physical and mental health comorbidity was more prevalent in women (6.33%; 95% CI, 6.3-6.4) than men (3.34%; 95% CI, 3.3-3.4) and approximately 50 times more prevalent among older persons than younger ones. Physical and mental health comorbidity was also twice as prevalent among people with lower secondary education than among those with postgraduate education. The presence of a mental health condition was strongly associated with the number of physical conditions; those with five or more physical conditions had an adjusted odds ratio for a mental health condition of 3.93 (95% CI, 3.8-4.1), compared to those with no physical conditions.

CONCLUSION

Multimorbidity prevalence and patterns in the Danish population are comparable to those of other European populations. The high prevalence of mental and physical health conditions highlights the need to ensure that healthcare systems deliver care that takes physical and mental comorbidity into account. Further, the higher prevalence of multimorbidity among persons with low educational attainment emphasizes the importance of having a health care system providing care that is beneficial to all regardless of socioeconomic status.

摘要

背景

欧洲各项研究中多重疾病的患病率各不相同,且使用了多种方法和定义。在本研究中,我们调查了丹麦人群中多重疾病的患病率与年龄、性别和教育程度的关系,以及身心健康状况与教育程度之间的关联。

方法

采用横断面设计,研究丹麦首都地区1,397,173名16岁及以上居民中多重疾病(定义为两种或更多慢性疾病)以及共病的身心健康状况在不同年龄组和教育程度水平中的患病率。计算患病率后,多重疾病和心理健康状况的优势比通过对性别、年龄、年龄平方、教育程度和身体疾病数量进行逻辑回归得出(仅用于心理健康状况的优势比)。针对每个变量的多重疾病和心理健康状况的优势比会根据所有其他变量进行调整。

结果

多重疾病患病率为21.6%。65岁及以上人群中有一半患有多重疾病,且患病率与教育程度呈负相关:初中及以下学历者中患病率为26.9%(95%可信区间,26.8 - 26.9),而研究生学历者中患病率为13.5%(95%可信区间,13.5 - 13.6)。与初中及以下学历者相比,研究生学历者多重疾病的调整后优势比为0.50(95%可信区间,0.49 - 0.51)。在所有人群中,4.9%(95%可信区间,4.9 - 4.9)患有身心健康疾病,在多重疾病患者中这一比例增至22.6%。身心健康共病在女性中(6.33%;95%可信区间,6.3 - 6.4)比男性中(3.34%;95%可信区间,3.3 - 3.4)更为普遍,且在老年人中比年轻人中普遍约50倍。身心健康共病在初中及以下学历者中也比研究生学历者中普遍两倍。心理健康状况的存在与身体疾病数量密切相关;与无身体疾病者相比,患有五种或更多身体疾病者心理健康状况的调整后优势比为3.93(95%可信区间,3.8 - 4.1)。

结论

丹麦人群中多重疾病的患病率和模式与其他欧洲人群相当。身心健康状况的高患病率凸显了确保医疗保健系统提供兼顾身心共病情况的护理的必要性。此外,低教育程度人群中多重疾病的较高患病率强调了拥有一个为所有人提供有益护理、不论社会经济地位的医疗保健系统的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2db/5424300/97c4ba49b8bb/12889_2017_4314_Fig1_HTML.jpg

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