Carlyle Molly, Rockliff Helen, Edwards Rachel, Ene Crina, Karl Anke, Marsh Beth, Hartley Lucie, Morgan Celia Ja
Psychopharmacology and Addiction Research Centre (PARC), College of Life and Environmental Science, University of Exeter, Exeter, UK.
Together Drug and Alcohol Services, Exeter, UK.
Subst Abuse. 2019 Apr 2;13:1178221819836726. doi: 10.1177/1178221819836726. eCollection 2019.
Opioid use disorder (OUD) is reaching epidemic proportions worldwide, and is notoriously difficult to treat. Compassion focused therapy (CFT) has emerged as therapeutic tool for treating individuals exhibiting high levels of self-criticism and low self-esteem, both of which are common in OUD. Until now, however, there had been no research investigating this therapy in patients with OUD. Before running a premature clinical trial, it is important to fully assess the feasibility and acceptability of this treatment in this group of individuals. We aimed to assess the feasibility of CFT treatment in individuals with OUD in a short group intervention, which was co-created by the research team, service users and a local drugs service. The intervention involved three 2-hour sessions held over 3 weeks, where participants engaged in compassion-orientated psychoeducation and self-compassionate exercises. Individuals were randomly assigned to either the CFT group (n = 15), the active control (relaxation) group (n = 12) or the waitlist control group (n = 11). Of 103 individuals approached, 45% attended a baseline visit suggesting the treatment was acceptable to this group. A relatively low attrition rate across the 3 groups was found for CFT (21.1%), with no difference in drop-out between the groups. Qualitative analysis of interviews with participants identified a desire for more sessions. Compassion focused therapy was thus feasible and well-tolerated in those with OUD, and a further trial to evaluate any clinical differences may be warranted.
阿片类药物使用障碍（OUD）在全球正呈流行态势，而且治疗难度极大。慈悲聚焦疗法（CFT）已成为一种治疗工具，用于治疗那些自我批评程度高且自尊水平低的个体，而这两种情况在阿片类药物使用障碍患者中很常见。然而，截至目前，尚无针对阿片类药物使用障碍患者进行该疗法研究的相关报道。在开展为时过早的临床试验之前，全面评估该治疗方法在这类个体中的可行性和可接受性非常重要。我们旨在通过一项由研究团队、服务使用者和当地戒毒服务机构共同设计的短期小组干预措施，评估慈悲聚焦疗法对阿片类药物使用障碍个体的治疗可行性。该干预措施包括在3周内进行的3次每次时长2小时的疗程，参与者要参与以慈悲为导向的心理教育和自我慈悲练习。个体被随机分配到慈悲聚焦疗法组（n = 15）、积极对照组（放松组，n = 12）或等待名单对照组（n = 11）。在被邀请的103名个体中，45%的人参加了基线访视，这表明该治疗方法为这组人所接受。慈悲聚焦疗法组在3组中的损耗率相对较低（21.1%），且各组间退出率无差异。对参与者访谈的定性分析表明他们希望增加疗程。因此，慈悲聚焦疗法对阿片类药物使用障碍患者来说是可行的且耐受性良好，或许有必要进一步开展试验以评估其临床差异。
