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脊髓刺激技术的发展及其在慢性疼痛管理中的临床意义。

Evolving Spinal Cord Stimulation Technologies and Clinical Implications in Chronic Pain Management.

机构信息

Valley Anesthesiology and Pain Consultants, Envision Physician Services, 645 E. Missouri Avenue, Suite 300, Phoenix, AZ, 85012, USA.

Department of Anesthesiology, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, USA.

出版信息

Curr Pain Headache Rep. 2019 May 1;23(6):39. doi: 10.1007/s11916-019-0778-9.

DOI:10.1007/s11916-019-0778-9
PMID:31044337
Abstract

PURPOSE OF REVIEW

Spinal cord stimulation (SCS), based on the gate theory of nociception, has been shown to be effective in the management of chronic pain conditions. While early-generation technology offered many patients improvement in their pain and symptoms, limitations including paresthesia, dependence on mapping, decreased chronological efficacy, and inadequate coverage left many patients with persistent pain and overt therapeutic failure.

RECENT FINDINGS

New advances in neuromodulation technology circumvent many of these previous limitations and offer patients improved pain relief and quality of life. In this review, an update on recent technological developments in the field of SCS and peripheral neuromodulation is presented with discussion on differentiating characteristics which may help guide applicability to individual patient needs.

摘要

目的综述

基于疼痛感觉门控理论的脊髓刺激(SCS)已被证明可有效治疗慢性疼痛病症。尽管早期技术为许多患者改善了疼痛和症状,但局限性包括感觉异常、依赖于映射、时效降低以及覆盖范围不足,导致许多患者仍存在持续疼痛和明显的治疗失败。

最新发现

神经调节技术的新进展规避了许多先前的局限性,并为患者提供了更好的疼痛缓解和生活质量。在这篇综述中,介绍了 SCS 和周围神经调节领域的最新技术进展,并讨论了有助于指导个体患者需求适用性的区分特征。

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Spinal Cord Stimulation for Neuropathic Pain: Current Trends and Future Applications.脊髓刺激治疗神经性疼痛:当前趋势与未来应用
Brain Sci. 2018 Jul 24;8(8):138. doi: 10.3390/brainsci8080138.
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Real-World Evaluation of Magnetic Resonance Imaging in Patients With a Magnetic Resonance Imaging Conditional Pacemaker System: Results of 4-Year Prospective Follow-Up in 2,629 Patients.磁共振成像条件性起搏器系统患者的真实世界评估:4 年前瞻性随访 2629 例患者的结果。
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Wireless high-frequency dorsal root ganglion stimulation for chronic low back pain: A pilot study.
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A Resonant Coupler for Subcutaneous Implant.皮下植入式谐振耦合器
Sensors (Basel). 2021 Dec 6;21(23):8141. doi: 10.3390/s21238141.
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Real-World Outcomes Using a Spinal Cord Stimulation Device Capable of Combination Therapy for Chronic Pain: A European, Multicenter Experience.使用能够进行联合治疗的脊髓刺激装置治疗慢性疼痛的真实世界疗效:一项欧洲多中心经验。
J Clin Med. 2021 Sep 10;10(18):4085. doi: 10.3390/jcm10184085.
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Deep Brain Stimulation of the Posterior Insula in Chronic Pain: A Theoretical Framework.慢性疼痛中后岛叶的深部脑刺激:一个理论框架。
Brain Sci. 2021 May 15;11(5):639. doi: 10.3390/brainsci11050639.
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Spinal cord fMRI with MB-SWIFT for assessing epidural spinal cord stimulation in rats.利用 MB-SWIFT 进行脊髓 fMRI 以评估大鼠硬膜外脊髓电刺激。
Magn Reson Med. 2021 Oct;86(4):2137-2145. doi: 10.1002/mrm.28844. Epub 2021 May 18.
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Brain fMRI during orientation selective epidural spinal cord stimulation.脑 fMRI 观察定向选择性硬膜外脊髓电刺激
Sci Rep. 2021 Mar 9;11(1):5504. doi: 10.1038/s41598-021-84873-8.
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Comparison of conventional, burst and high-frequency spinal cord stimulation on pain relief in refractory failed back surgery syndrome patients: study protocol for a prospective randomized double-blinded cross-over trial (MULTIWAVE study).常规、爆发式和高频脊髓刺激治疗难治性失败性腰椎手术综合征患者疼痛的比较:前瞻性随机双盲交叉试验(MULTIWAVE 研究)研究方案。
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无线高频背根神经节刺激治疗慢性腰痛:一项初步研究。
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BMC Surg. 2018 Mar 27;18(1):18. doi: 10.1186/s12893-018-0349-8.
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Neuromodulation. 2018 Dec;21(8):787-792. doi: 10.1111/ner.12767. Epub 2018 Mar 25.
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