纵隔毛霉菌病：病例报告、文献复习及连续脂质体两性霉素 B 灌洗治疗。
Mediastinal Mucormycosis: Case report, review of literature and treatment with continuous liposomal amphotericin B irrigation.
机构信息
Division of Infectious Diseases, Department of Medicine, Montefiore Medical Center and Albert Einstein College of Medicine, The Bronx, New York.
Division of Hospital Medicine, Department of Medicine, Geisinger Medical Center, Danville, Pennsylvania.
出版信息
Mycoses. 2019 Sep;62(9):739-745. doi: 10.1111/myc.12922. Epub 2019 May 23.
Mediastinal mucormycosis is an uncommon but lethal infection associated with an 83% mortality. We describe a case of fatal Rhizopus microsporus mediastinitis despite three exploratory mediastinal surgeries and complementary systemic and mediastinal irrigation with liposomal amphotericin B. We further review the literature on surgical and antifungal management of mediastinal mucormycosis.
纵隔毛霉菌病是一种罕见但致命的感染，死亡率为 83%。我们描述了一例致命的小孢根霉纵隔炎病例，尽管进行了三次纵隔探查手术，并辅以系统和纵隔注射脂质体两性霉素 B 进行辅助治疗。我们进一步回顾了纵隔毛霉菌病的手术和抗真菌治疗的文献。
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