Benito Antonio, Bueno Juan M, Pérez Guillermo M, Artal Pablo
J Opt Soc Am A Opt Image Sci Vis. 2019 Apr 1;36(4):B138-B142. doi: 10.1364/JOSAA.36.00B138.
Tear-film dynamics were analyzed by a synchronizing recording of double-pass (DP) and pupil retro-illumination (RI) images with contrast sensitivity (CS) measurements. Simultaneous DP and RI images were acquired in three subjects wearing contact lenses while keeping the eye open. Changes in contrast sensitivity for an 18 c/deg green grating were also estimated. From the DP retinal images, the effect of the tear film is described through the objective scattering index (OSI). This presented a negative correlation with the increase in CS during tear-film deterioration (as observed by RI imaging). These results show a relationship between visual outcome degradation due to tear-film breakup and the increase in intraocular scattering. This work shows a combined methodology for the evaluation of tear-film dynamics.
通过同步记录双程（DP）和瞳孔后向照明（RI）图像以及测量对比敏感度（CS）来分析泪膜动力学。在三名佩戴隐形眼镜且眼睛睁开的受试者中采集了同步的DP和RI图像。还估计了18 c/deg绿色光栅的对比敏感度变化。从DP视网膜图像中，通过客观散射指数（OSI）描述泪膜的影响。这与泪膜恶化期间CS的增加呈负相关（如通过RI成像观察到的）。这些结果表明泪膜破裂导致的视觉结果下降与眼内散射增加之间存在关联。这项工作展示了一种评估泪膜动力学的综合方法。
