Baylor College of Medicine, Department of Emergency Medicine, Ben Taub General Hospital, Houston, TX, USA.
Baylor College of Medicine, Department of Emergency Medicine, Ben Taub General Hospital, Houston, TX, USA.
Am J Emerg Med. 2020 Jan;38(1):105-108. doi: 10.1016/j.ajem.2019.04.036. Epub 2019 Apr 22.
Although there is no consensus on how to use an electrocardiogram (ECG) in patients with hyperkalemia, physicians often obtain it in the acute setting when diagnosing and treating hyperkalemia. The objective of this study is to evaluate if physicians are able to detect hyperkalemia based on the ECG.
The study was conducted at a large county hospital with a population of end stage renal disease (ESRD) patients who received hemodialysis (HD) solely on an emergent basis. Five hundred twenty eight ECGs from ESRD patients were evaluated. The prevalence of hyperkalemia was approximately 60% in this cohort, with at least half of them in the severe hyperkalemia range (K ≥ 6.5 mEq/L).
The mean sensitivity and specificity of the emergency physicians detecting hyperkalemia were 0.19 (± 0.16) and 0.97(± 0.04) respectively. The mean positive predictive value of evaluators for detecting hyperkalemia was 0.92 (±0.13) and the mean negative predictive value was 0.46 (± 0.05). In severe hyperkalemia (K ≥ 6.5 mEq/L), the mean sensitivity improved to 0.29 (± 0.20), while specificity decreased to 0.95 (±0.07).
An ECG is not a sensitive method of detecting hyperkalemia and should not be relied upon to rule it out. However, the ECG has a high specificity for detecting hyperkalemia and could be used as a rule in test.
尽管在高钾血症患者中如何使用心电图(ECG)尚无共识,但在诊断和治疗高钾血症时,医生通常会在急性情况下获得心电图。本研究的目的是评估医生是否能够根据心电图检测到高钾血症。
该研究在一家拥有大量终末期肾病(ESRD)患者的县级医院进行,这些患者仅因紧急情况接受血液透析(HD)。评估了 528 名 ESRD 患者的心电图。该队列中高钾血症的患病率约为 60%,其中至少有一半处于严重高钾血症范围(K≥6.5 mEq/L)。
急诊医师检测高钾血症的平均敏感性和特异性分别为 0.19(±0.16)和 0.97(±0.04)。评估者检测高钾血症的阳性预测值平均值为 0.92(±0.13),阴性预测值平均值为 0.46(±0.05)。在严重高钾血症(K≥6.5 mEq/L)中,平均敏感性提高至 0.29(±0.20),而特异性降低至 0.95(±0.07)。
心电图不是检测高钾血症的敏感方法,不应依靠它来排除高钾血症。然而,心电图对检测高钾血症具有很高的特异性,可作为检验规则。