Interdisciplinary Center for Aquaculture Research, Laboratory of Biotechnology and Aquatic Genomics, Department of Oceanography, Universidad de Concepción, Concepción, Chile.
Interdisciplinary Center for Aquaculture Research, Laboratory of Biotechnology and Aquatic Genomics, Department of Oceanography, Universidad de Concepción, Concepción, Chile.
Fish Shellfish Immunol. 2019 Jul;90:199-209. doi: 10.1016/j.fsi.2019.04.065. Epub 2019 Apr 30.
The study of host-parasite relationships is an integral part of the immunology of aquatic species, where the complexity of both organisms has to be overlayed with the lifecycle stages of the parasite and immunological status of the host. A deep understanding of how the parasite survives in its host and how they display molecular mechanisms to face the immune system can be applied for novel parasite control strategies. This review highlights current knowledge about salmon and sea louse, two key aquatic animals for aquaculture research worldwide. With the aim to catch the complexity of the salmon-louse interactions, molecular information gleaned through genomic studies are presented. The host recognition system and the chemosensory receptors found in sea lice reveal complex molecular components, that in turn, can be disrupted through specific molecules such as non-coding RNAs.
宿主-寄生虫关系的研究是水生物种免疫学的一个组成部分，其中必须将两种生物体的复杂性与寄生虫的生命周期阶段和宿主的免疫状态叠加在一起。深入了解寄生虫如何在宿主中生存以及它们如何显示分子机制来应对免疫系统，可以应用于新型寄生虫控制策略。 本综述重点介绍了鲑鱼和海虱的最新知识，这两种动物是全球水产养殖研究的关键。 为了捕捉鲑鱼-海虱相互作用的复杂性，通过基因组研究获得的分子信息被呈现出来。 在海虱中发现的宿主识别系统和化学感觉受体揭示了复杂的分子成分，这些成分反过来又可以通过非编码 RNA 等特定分子被破坏。
