Colombo N, Sessa C, Bois A du, Ledermann J, McCluggage W G, McNeish I, Morice P, Pignata S, Ray-Coquard I, Vergote I, Baert T, Belaroussi I, Dashora A, Olbrecht S, Planchamp F, Querleu D
Division of Medical Gynecologic Oncology, European Institute of Oncology IRCCS, University of Milan-Bicocca, Milan, Italy
Department of Medical Oncology, Oncology Institute of Southern Switzerland, Ospedale San Giovanni, Bellinzona, Switzerland.
Int J Gynecol Cancer. 2019 May 7;29(4):728-760. doi: 10.1136/ijgc-2019-000308.
The development of guidelines is one of the core activities of the European Society for Medical Oncology (ESMO) and European Society of Gynaecologial Oncology (ESGO), as part of the mission of both societies to improve the quality of care for patients with cancer across Europe. ESMO and ESGO jointly developed clinically relevant and evidence-based recommendations in several selected areas in order to improve the quality of care for women with ovarian cancer. The ESMO-ESGO consensus conference on ovarian cancer was held on April 12-14, 2018 in Milan, Italy, and comprised a multidisciplinary panel of 40 leading experts in the management of ovarian cancer. Before the conference, the expert panel worked on five clinically relevant questions regarding ovarian cancer relating to each of the following four areas: pathology and molecular biology, early-stage and borderline tumours, advanced stage disease and recurrent disease. Relevant scientific literature, as identified using a systematic search, was reviewed in advance. During the consensus conference, the panel developed recommendations for each specific question and a consensus was reached. The recommendations presented here are thus based on the best available evidence and expert agreement. This article presents the recommendations of this ESMO-ESGO consensus conference, together with a summary of evidence supporting each recommendation.
制定指南是欧洲医学肿瘤学会(ESMO)和欧洲妇科肿瘤学会(ESGO)的核心活动之一,这也是两个学会在全欧洲提高癌症患者护理质量使命的一部分。ESMO和ESGO在几个选定领域联合制定了具有临床相关性且基于证据的建议,以提高卵巢癌女性患者的护理质量。卵巢癌ESMO-ESGO共识会议于2018年4月12日至14日在意大利米兰举行,由40位卵巢癌管理领域的顶尖专家组成的多学科小组参与。会议前,专家小组针对卵巢癌就以下四个领域中的每一个领域提出了五个与临床相关的问题:病理学和分子生物学、早期和交界性肿瘤、晚期疾病和复发性疾病。通过系统检索确定的相关科学文献提前进行了审查。在共识会议期间,小组针对每个具体问题制定了建议并达成了共识。因此,这里提出的建议基于现有最佳证据和专家共识。本文介绍了此次ESMO-ESGO共识会议的建议,以及支持每项建议的证据总结。