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Generating Mechanically Stable, Pediatric, and Scaffold-Free Nasal Cartilage Constructs In Vitro.体外生成机械稳定、适合儿科且无支架的鼻软骨构建体。
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Reconstruction of Alar Nasal Cartilage Defects Using a Tissue Engineering Technique Based on a Combined Use of Autologous Chondrocyte Micrografts and Platelet-rich Plasma: Preliminary Clinical and Instrumental Evaluation.基于自体软骨细胞微移植和富血小板血浆联合应用的组织工程技术修复鼻翼软骨缺损:初步临床和仪器评估
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Engineered autologous cartilage tissue for nasal reconstruction after tumour resection: an observational first-in-human trial.肿瘤切除后用于鼻重建的工程化自体软骨组织:首例人体观察性试验。
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组织工程在鼻科学中的临床应用

Clinical Applications for Tissue Engineering in Rhinology.

作者信息

Prokopakis Emmanuel, Doulaptsi Maria, Karatzanis Alexander, Kawauchi Hideyuki

机构信息

Department of Otorhinolaryngology - Head and Neck Surgery, University of Crete School of Medicine, Crete, Greece.

Department of Otorhinolaryngology, University of Shimane School of Medicine, Shimane, Japan.

出版信息

Turk Arch Otorhinolaryngol. 2019 Mar;57(1):39-41. doi: 10.5152/tao.2019.3889. Epub 2019 Mar 1.

DOI:10.5152/tao.2019.3889
PMID:31049252
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6461332/
Abstract

Tissue engineering implies a number of established techniques in several fields in medicine. A thorough review of current clinical applications for tissue engineering in rhinology is addressed. Current status, as well as, published in vivo studies is presented. Moreover, relevant clinical applications and future perspectives of tissue engineering are demonstrated. There is a lack of high quality clinical studies in the literature regarding the role of tissue engineering in the rhinology field. Further research is needed to translate this concept from bench to bedside.

摘要

组织工程涉及医学多个领域的一些成熟技术。本文对组织工程在鼻科学中的当前临床应用进行了全面综述。介绍了其现状以及已发表的体内研究。此外,还展示了组织工程的相关临床应用和未来前景。关于组织工程在鼻科学领域的作用,文献中缺乏高质量的临床研究。需要进一步研究将这一概念从实验室转化到临床应用。