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用于治疗干性疼痛性牙槽炎(“干槽症”)的敷料研究。第3部分:甘露醇和山梨醇对含乙酰水杨酸、甲芬那酸和防腐素P的片剂及敷料性质的影响。

Investigation of dressings designed for treatment of alveolitis sicca dolorosa ("dry socket"). Part 3: Influence of mannitol and sorbitol on properties of tablets and dressings comprising acetylsalicylic acid, mefenamic acid and aseptin P.

作者信息

Grabowska-Bochenek J, Kubis A

出版信息

Pharmazie. 1986 Nov;41(11):782-3.

PMID:3104934
Abstract

In the dressings for dry tooth sockets, mannitol and sorbitol as solid hydrophilizers have been applied. Increase of concentrations of these hydrophilizers in the tablets results in dressings with increased swelling ability and pharmaceutical availability but decreased viscosity and resistance to washing out. These properties of the dressings are also influenced by medicinal substances present. The dressing fills the tooth socket within several min, removes pain and remain there for 24-48 h.

摘要

在干槽症敷料中,已应用甘露醇和山梨醇作为固体亲水剂。片剂中这些亲水剂浓度的增加会导致敷料的膨胀能力和药物可利用性提高,但粘度降低且耐冲洗性下降。敷料的这些特性也受所存在药物物质的影响。该敷料在几分钟内就能填充牙槽窝,消除疼痛,并在那里停留24至48小时。

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