乳牙的显微硬度和铅（Pb）水平。
Primary teeth microhardness and lead (Pb) levels.
作者信息
Foxman Betsy, Kolderman Ethan, Salzman Elizabeth, Cronenwett Anna, Gonzalez-Cabezas Carlos, Neiswanger Katherine, Marazita Mary L
机构信息
Center for Molecular and Clinical Epidemiology of Infectious Diseases, Department of Epidemiology, University of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, Michigan, 48109, USA.
University of Michigan School of Dentistry, 101 N. University Ave, Ann Arbor, Michigan, 48109, USA.
出版信息
Heliyon. 2019 Apr 24;5(4):e01551. doi: 10.1016/j.heliyon.2019.e01551. eCollection 2019 Apr.
OBJECTIVES
Lead (Pb) exposure is associated with dental caries. Whether Pb affects tooth microhardness, is unclear. Our objective was to assess whether Pb concentration is associated with microhardness.
METHODS
Exfoliated primary teeth were collected from 46 volunteers. Teeth were sectioned, one half of each tooth was tested for enamel Knoop microhardness. The remaining half was digested and Pb measured using an inductively coupled plasma-mass spectrometer.
RESULTS
The correlations between Pb levels and microhardness were very low, and were not statistically significant at p < 0.05.
CONCLUSIONS
Previous exposure to high levels of Pb was not associated with decreased tooth microhardness.
CLINICAL SIGNIFICANCE
This study assessed whether Pb in deciduous teeth is associated with tooth microhardness. As this was not the case, further studies are needed to identify the mechanisms behind the association between lead exposure and tooth decay.
目的
铅（Pb）暴露与龋齿有关。铅是否会影响牙齿的显微硬度尚不清楚。我们的目的是评估铅浓度是否与显微硬度相关。
方法
从46名志愿者中收集脱落的乳牙。将牙齿切片，每颗牙齿的一半用于测试釉质努氏显微硬度。另一半进行消化处理，并用电感耦合等离子体质谱仪测量铅含量。
结果
铅含量与显微硬度之间的相关性非常低，在p<0.05时无统计学意义。
结论
既往高铅暴露与牙齿显微硬度降低无关。
临床意义
本研究评估了乳牙中的铅是否与牙齿显微硬度相关。由于并非如此，因此需要进一步研究以确定铅暴露与龋齿之间关联背后的机制。
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