Department of Endocrinology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Diabetes Obes Metab. 2019 Aug;21(8):1801-1816. doi: 10.1111/dom.13760. Epub 2019 Jun 17.
Traditional Chinese medicine (TCM) has recorded knowledge of diabetes for over 2000 years. Because a considerable number of TCM studies exhibit design defects, such as limited intervention duration, small sample sizes and inconsistent efficacy evaluations, the role of TCM in the treatment of diabetes cannot be fully elucidated. In this review, we evaluate randomized controlled trials of prediabetes, diabetes and diabetic complications published in the past decade. We found that TCM could significantly improve glucose control and clinical indices in patients with diabetes and effectively delay the progression of diabetes. We also summarize potential pharmacological mechanisms underlying the efficacy of TCM medication/herbs and their active ingredients for treating diabetes. More rigorously designed experiments and long-term evaluation of TCM for diabetes will allow for more effective diabetes management.
中医（TCM）对糖尿病的认识已有 2000 多年的历史。由于相当数量的 TCM 研究存在设计缺陷，如干预持续时间有限、样本量小以及疗效评估不一致，因此无法充分阐明 TCM 在糖尿病治疗中的作用。在这篇综述中，我们评估了过去十年中发表的关于糖尿病前期、糖尿病和糖尿病并发症的随机对照试验。我们发现，TCM 可显著改善糖尿病患者的血糖控制和临床指标，并有效延缓糖尿病的进展。我们还总结了 TCM 药物/草药及其活性成分治疗糖尿病的潜在药理机制。更严格设计的实验和对 TCM 治疗糖尿病的长期评估将有助于更有效地管理糖尿病。
